Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 15/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14007184 | 0.93 | MET (0.36) | NOS1MAPK14MET | |
| SCHEMBL14007180 | 0.88 | MAPK14 (0.39) | NOS1MAPK14SCN9AMAPK1MET | |
| SCHEMBL14007177 | 0.84 | NOS1 (0.38) | NOS1MAPK14MAPK1SGK1MET | |
| SCHEMBL14007181 | 0.81 | MET (0.35) | NOS1MAPK14MET | |
| SCHEMBL5321926 | 0.79 | MAPK14 (0.32) | MAPK14 | |
| SCHEMBL5321924 | 0.79 | MAPK14 (0.32) | MAPK14 | |
| SCHEMBL4918755 | 0.79 | NOS1 (0.46) | NOS1MAPK1SGK1MET | |
| SCHEMBL14007182 | 0.77 | MAP4K4 (0.39) | NOS1MAPK14MET | |
| SCHEMBL14007178 | 0.75 | MAP4K4 (0.39) | NOS1MAPK14MAPK1SGK1MET | |
| SCHEMBL4927202 | 0.71 | NOS1 (0.41) | NOS1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280766-A1 | Pyridopyrazines for Combating Phytopathogenic Fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-13 | — | — | US | disclosed |
| US-20080280766-A1 | Pyridopyrazines for Combating Phytopathogenic Fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-13 | — | — | US | disclosed |
| US-20080280766-A1 | Pyridopyrazines for Combating Phytopathogenic Fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-13 | — | — | US | disclosed |
| EP-1758901-A1 | PYRIDOPYRAZINES FOR COMBATTING PHYTOPATHOGENIC FUNGI | Syngeta Participations AG (CH) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123733-A1 | PYRIDOPYRAZINES FOR COMBATTING PHYTOPATHOGENIC FUNGI | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280766-A1 | Pyridopyrazines for Combating Phytopathogenic Fungi | Q6ZSR9, GRHPR, PRXL2A | NOS1 1227/4885MAPK14 2837/4885SCN9A 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.