Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924218 | 0.90 | CCR5 (0.49) | CCR5SMN1; SMN2LMNAKCNH2ALDH1A1 | |
| SCHEMBL4920726 | 0.90 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1KDM4EPOLB | |
| SCHEMBL4922446 | 0.89 | CCR5 (0.49) | CCR5SMN1; SMN2LMNAKCNH2ALDH1A1 | |
| SCHEMBL4921856 | 0.89 | CCR5 (0.49) | CCR5SMN1; SMN2LMNAKCNH2ALDH1A1 | |
| SCHEMBL4924890 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAALDH1A1KDM4EPOLB | |
| SCHEMBL4921979 | 0.89 | ALDH1A1 (0.56) | SMN1; SMN2LMNAALDH1A1KDM4EHTT | |
| SCHEMBL4916484 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAKCNH2ALDH1A1KDM4E | |
| SCHEMBL4923881 | 0.87 | LMNA (0.49) | SMN1; SMN2LMNAALDH1A1KDM4EPOLB | |
| SCHEMBL4924914 | 0.87 | LMNA (0.49) | SMN1; SMN2LMNAALDH1A1KDM4EPOLB | |
| SCHEMBL4924246 | 0.87 | KDM4E (0.52) | SMN1; SMN2LMNAALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081824-A1 | Substituted piperidines as modulators of chemokine receptor activity | CCR1, CCR3, CCR2 | CCR5 4/4885SMN1; SMN2 3688/4885LMNA 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.