Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925317 | 0.76 | — | — | |
| SCHEMBL10976864 | 0.72 | — | — | |
| SCHEMBL18455323 | 0.68 | — | — | |
| SCHEMBL1193338 | 0.67 | — | — | |
| SCHEMBL10341220 | 0.67 | ALDH1A1 (0.34) | — | |
| Carbon Monoxide SCHEMBL11839192 | 0.66 | — | — | |
| SCHEMBL10980701 | 0.65 | PSMB1 (0.43) | TSHR | |
| SCHEMBL11145659 | 0.64 | MAOB (0.38) | TSHRMAPK1 | |
| Bromide SCHEMBL11678467 | 0.64 | ALDH1A1 (0.33) | — | |
| SCHEMBL13948860 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877956-B2 | 1,3,2-dioxaphosphorinane, 2-sulfide derivatives for use as anti-wear additives in lubricant compositions | AFTON CHEMICAL CORPORATION (US) | 2014-11-04 | — | — | US | disclosed |
| US-8871696-B2 | 1,3,2-dioxaphosphorinane, 2-sulfide derivatives for use as anti-wear additives in lubricant compositions | AFTON CHEMICAL CORPORATION (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140066646-A1 | 1,3,2-Dioxaphosphorinane, 2-Sulfide Derivatives For Use As Anti-Wear Additives In Lubricant Compositions | AFTON CHEMICAL CORPORATION (US) | 2014-03-06 | — | — | US | disclosed |
| US-20140066346-A1 | 1,3,2-Dioxaphosphorinane, 2-Sulfide Derivatives For Use As Anti-Wear Additives In Lubricant Compositions | AFTON CHEMICAL CORPORATION (US) | 2014-03-06 | — | — | US | disclosed |
| US-8618030-B2 | 1,3,2-dioxaphosphorinane, 2-sulfide derivatives for use as anti-wear additives in lubricant compositions | AFTON CHEMICAL CORPORATION (US) | 2013-12-31 | — | — | US | disclosed |
| US-20130281337-A1 | 1,3,2-Dioxaphosphorinane, 2-Sulfide Derivatives For Use As Anti-Wear Additives In Lubricant Compositions | AFTON CHEMICAL CORPORATION | 2013-10-24 | — | — | US | disclosed |
| US-8466096-B2 | 1,3,2-dioxaphosphorinane, 2-sulfide derivatives for use as anti-wear additives in lubricant compositions | AFTON CHEMICAL CORPORATION (US) | 2013-06-18 | — | — | US | disclosed |
| US-20080269088-A1 | non-acidic, sulfur-containing, phosphorus-containing compound of the formula Such a compound may exhibit improved antiwear performance and thermal stability in lubricating compositions. | AFTON CHEMICAL CORPORATION | 2008-10-30 | — | — | US | disclosed |
| US-6242658-B1 | INVOLVING NICKEL METALLACYCLES (NICKEL TRINEOPENTYLPHOSPHITE)WITH PHOSPHITE LIGANDS | E. I. DUPONT DE NEMOURS AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0889867-A1 | PROCESS FOR THE MANUFACTURE OF FLUORINE-SUBSTITUTED HYDROCARBONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997035820-A1 | PROCESS FOR THE MANUFACTURE OF FLUORINE-SUBSTITUTED HYDROCARBONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269088-A1 | non-acidic, sulfur-containing, phosphorus-containing compound of the formula Such a compound may exhibit improved antiwear performance and thermal stability in lubricating compositions. | PSPH, PNISR, SRSF1 | TSHR 2304/4885MAPK1 672/4885 |
| US-20140066646-A1 | 1,3,2-Dioxaphosphorinane, 2-Sulfide Derivatives For Use As Anti-Wear Additives In Lubricant Compositions | PRDX1, PSPH, PRDX4 | TSHR 1768/4885MAPK1 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.