Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | NEK2 | P51955 | 1/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744554 | 0.77 | MAPT (0.53) | MAPTTDP1ALDH1A1SMN1; SMN2ERN1 | |
| SCHEMBL3396242 | 0.74 | MAPT (0.53) | MAPTTDP1ALDH1A1SMN1; SMN2ERN1 | |
| SCHEMBL27288856 | 0.74 | SMN1; SMN2 (0.51) | MAPTTDP1ALDH1A1SMN1; SMN2ERN1 | |
| SCHEMBL8951248 | 0.74 | MAPT (0.44) | MAPTTDP1ALDH1A1SMN1; SMN2ERN1 | |
| SCHEMBL1757653 | 0.70 | MAPT (0.33) | MAPTTDP1ALDH1A1SMN1; SMN2GPR3 | |
| SCHEMBL4924273 | 0.69 | ALDH1A1 (1.00) | MAPTTDP1ALDH1A1SMN1; SMN2ERN1 | |
| SCHEMBL4655299 | 0.69 | MAPT (0.66) | MAPTTDP1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL23323175 | 0.68 | MEN1 (0.42) | SMN1; SMN2 | |
| SCHEMBL30683723 | 0.68 | ERN1 (0.48) | MAPTTDP1ALDH1A1SMN1; SMN2ERN1 | |
| SCHEMBL30078318 | 0.68 | MEN1 (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968641-B1 | PRODUCTION OF CONJUGATES | INNOVA BIOSCIENCES LTD (GB) | 2014-06-11 | — | — | EP | disclosed |
| US-20130295641-A1 | Production of Conjugates | INNOVA BIOSCIENCES LTD (GB) | 2013-11-07 | — | — | US | disclosed |
| US-8492129-B2 | Production of conjugates | INNOVA BIOSCIENCES, LTD. (GB) | 2013-07-23 | — | — | US | disclosed |
| US-20080299637-A1 | Production of Conjugates | ABCAM LIMITED (GB) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299637-A1 | Production of Conjugates | GSTA2, TST, GSTK1 | MAPT 4496/4885TDP1 4131/4885ALDH1A1 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.