Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL4924857 | 1.00 | CA1 (0.32) | CA1CA9HCAR2ATMBBOX1 | |
| Potassium Ion SCHEMBL4926876 | 1.00 | CA1 (0.32) | CA1CA9HCAR2ATMBBOX1 | |
| SCHEMBL4584052 | 0.88 | HCAR2 (0.38) | HCAR2ATMALDH1A1TSHRTDP1 | |
| SCHEMBL9561364 | 0.88 | HCAR2 (0.38) | HCAR2ATMALDH1A1TSHRTDP1 | |
| SCHEMBL4584048 | 0.88 | HCAR2 (0.38) | HCAR2ATMALDH1A1TSHRTDP1 | |
| SCHEMBL9561368 | 0.80 | HCAR2 (0.52) | HCAR2ATMALDH1A1TSHRTDP1 | |
| SCHEMBL9860820 | 0.80 | HCAR2 (0.52) | HCAR2ATMALDH1A1TSHRTDP1 | |
| SCHEMBL9561373 | 0.80 | HCAR2 (0.52) | HCAR2ATMALDH1A1TSHRTDP1 | |
| SCHEMBL15243104 | 0.78 | ALDH1A1 (0.33) | HCAR2ATMALDH1A1TSHRTDP1 | |
| SCHEMBL9070548 | 0.78 | ALDH1A1 (0.33) | HCAR2ATMALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312351-A1 | Tetraalkylammonium Carboxylate Salts as Trimerization Catalysts for Spray Foam Applications | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2008-12-18 | — | — | US | claimed |
| EP-2003157-A2 | Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications | Air Products and Chemicals, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| US-20080312351-A1 | Tetraalkylammonium Carboxylate Salts as Trimerization Catalysts for Spray Foam Applications | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2008-12-18 | — | — | US | disclosed |
| EP-2003157-A2 | Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications | Air Products and Chemicals, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |