Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.42 |
| ▸ | THRA | P10827 | 12/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932486 | 0.90 | THRB (0.45) | THRBTHRALMNAMRGPRX4MAPT | |
| SCHEMBL5717763 | 0.90 | HSD17B10 (0.37) | THRBTHRALMNAS1PR2S1PR1 | |
| SCHEMBL5717899 | 0.89 | THRB (0.54) | THRBTHRAS1PR2S1PR1S1PR3 | |
| SCHEMBL4932176 | 0.89 | THRB (0.41) | THRBTHRAS1PR2S1PR1S1PR3 | |
| SCHEMBL4927179 | 0.89 | THRB (0.41) | THRBTHRAS1PR2S1PR1S1PR3 | |
| SCHEMBL4931911 | 0.88 | THRA (0.49) | THRBTHRALMNA | |
| SCHEMBL4935573 | 0.86 | PPARD (0.45) | THRBTHRAMRGPRX4PPARD | |
| SCHEMBL4933395 | 0.86 | THRB (0.52) | THRBTHRAMRGPRX4MAPTMEN1 | |
| SCHEMBL4929467 | 0.85 | MRGPRX4 (0.40) | THRBTHRAS1PR2S1PR1S1PR3 | |
| SCHEMBL4932487 | 0.85 | MEN1 (0.37) | THRBTHRALMNAMRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | THRB 4/4885THRA 3/4885LMNA 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.