Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 6/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 4/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931818 | 0.92 | PPARD (0.46) | PPARDTRPA1THRBMRGPRX4THRA | |
| SCHEMBL5717974 | 0.91 | TRPA1 (0.42) | PPARDTRPA1CYP1A2THRBMRGPRX4 | |
| SCHEMBL4928689 | 0.89 | THRA (0.50) | TRPA1CYP1A2THRBMRGPRX4THRA | |
| SCHEMBL4932092 | 0.89 | THRB (0.51) | TRPA1CYP1A2THRBTHRARXRA | |
| SCHEMBL4929395 | 0.88 | PPARD (0.47) | PPARDTHRBMRGPRX4THRARXRA | |
| SCHEMBL4925262 | 0.86 | THRB (0.42) | PPARDTHRBMRGPRX4THRA | |
| SCHEMBL4931483 | 0.86 | TRPA1 (0.47) | TRPA1CYP1A2MRGPRX4SMN1; SMN2 | |
| SCHEMBL5107813 | 0.86 | THRB (0.46) | PPARDTHRBMRGPRX4THRARXRA | |
| SCHEMBL5108768 | 0.86 | PPARD (0.46) | PPARDTHRBMRGPRX4THRARXRA | |
| SCHEMBL4923914 | 0.85 | TRPA1 (0.42) | PPARDTRPA1CYP1A2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | PPARD 284/4885TRPA1 675/4885CYP1A2 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.