Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 3/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 5/20 | 0.55 |
| ▸ | MMP9 | P14780 | 5/20 | 0.55 |
| ▸ | MMP13 | P45452 | 5/20 | 0.55 |
| ▸ | MMP7 | P09237 | 4/20 | 0.55 |
| ▸ | MMP2 | P08253 | 3/20 | 0.55 |
| ▸ | MMP3 | P08254 | 3/20 | 0.55 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025842 | 1.00 | ADAM17 (0.60) | ADAM17SLC1A3SLC1A2SLC1A1MMP1 | |
| SCHEMBL1770811 | 0.91 | MMP1 (0.67) | ADAM17SLC1A3SLC1A2SLC1A1MMP1 | |
| SCHEMBL12649188 | 0.91 | MMP1 (0.67) | ADAM17SLC1A3SLC1A2SLC1A1MMP1 | |
| SCHEMBL609430 | 0.83 | SLC1A3 (0.51) | ADAM17SLC1A3SLC1A2SLC1A1MMP1 | |
| SCHEMBL14025844 | 0.83 | MMP1 (0.54) | ADAM17MMP1MMP9MMP13MMP7 | |
| SCHEMBL4915080 | 0.83 | MMP1 (0.54) | ADAM17MMP1MMP9MMP13MMP7 | |
| SCHEMBL14045868 | 0.83 | SLC1A3 (0.60) | ADAM17SLC1A3SLC1A2SLC1A1MMP9 | |
| SCHEMBL609429 | 0.82 | LARS1 (0.50) | ADAM17SLC1A3SLC1A2SLC1A1MMP1 | |
| SCHEMBL4927229 | 0.81 | MMP1 (0.47) | ADAM17MMP1MMP9MMP13MMP7 | |
| SCHEMBL5182142 | 0.81 | MMP1 (0.47) | ADAM17MMP1MMP9MMP13MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2008-10-30 | — | — | US | disclosed |
| US-20070066646-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | AOC2, AOC3, AOC1 | ADAM17 1884/4885SLC1A3 217/4885SLC1A2 434/4885 |
| US-20070066646-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | AOC2, AOC3, AOC1 | ADAM17 2174/4885SLC1A3 217/4885SLC1A2 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.