SCHEMBL14045868

SCHEMBL14045868

CC(O)C(NS(=O)(=O)c1ccc2ccccc2c1)C(=O)ON

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.60
SLC1A2 P43004 1/20 0.60
SLC1A1 P43005 1/20 0.60
LARS1 Q9P2J5 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
F2 P00734 5/20 0.47
PRSS1 P07477 2/20 0.47
PRSS2 P07478 2/20 0.47
PRSS3 P35030 2/20 0.47
ADAMTS4 O75173 1/20 0.47
MMP13 P45452 1/20 0.47
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2C9 P11712 2/20 0.47
TSHR P16473 2/20 0.47
CYP2C19 P33261 2/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
KAT6A Q92794 2/20 0.46
ALDH1A1 P00352 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14045787 0.83 SLC1A3 (0.42) SLC1A3SLC1A2SLC1A1ADAMTS4MMP13
SCHEMBL14025842 0.83 ADAM17 (0.60) SLC1A3SLC1A2SLC1A1LARS1L3MBTL1
SCHEMBL4925808 0.83 ADAM17 (0.60) SLC1A3SLC1A2SLC1A1LARS1L3MBTL1
SCHEMBL14045735 0.82 SLC1A3 (0.41) SLC1A3SLC1A2SLC1A1F2PRSS1
SCHEMBL14045736 0.82 ADAMTS4 (0.64) SLC1A3SLC1A2SLC1A1ADAMTS4MMP13
SCHEMBL14045830 0.80 SLC1A3 (0.57) SLC1A3SLC1A2SLC1A1MMP13TSHR
SCHEMBL14045891 0.80 SLC1A3 (0.53) SLC1A3SLC1A2SLC1A1LARS1L3MBTL1
SCHEMBL8529829 0.79 SLC1A3 (0.73) SLC1A3SLC1A2SLC1A1ADAMTS4MMP13
SCHEMBL6979084 0.79 SLC1A3 (0.73) SLC1A3SLC1A2SLC1A1ADAMTS4MMP13
SCHEMBL1771358 0.78 SLC1A3 (0.54) SLC1A3SLC1A2SLC1A1LARS1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof GENMEDICA THERAPEUTICS SL (ES) 2008-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269282-A1 Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof AOC2, AOC3, AOC1 SLC1A3 217/4885SLC1A2 434/4885SLC1A1 169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.