Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 10/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 2/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493208 | 0.94 | GRM5 (0.37) | GRM5TACR1TACR2PTGIRBDKRB1 | |
| SCHEMBL493688 | 0.92 | PTGIR (0.37) | PTGIRBDKRB1FAAHBCHEACHE | |
| SCHEMBL493804 | 0.91 | BDKRB1 (0.38) | PTGIRBDKRB1FAAHBCHEACHE | |
| SCHEMBL493360 | 0.90 | LMNA (0.39) | TACR1TACR2BDKRB1SLC6A9 | |
| SCHEMBL493387 | 0.88 | GRM5 (0.36) | GRM5TACR1TACR2PTGIRBDKRB1 | |
| SCHEMBL492623 | 0.86 | NAPEPLD (0.36) | PTGIRBDKRB1FAAHBCHEACHE | |
| SCHEMBL492927 | 0.85 | CACNA2D1 (0.36) | PTGIRBDKRB1FAAHBCHEACHE | |
| SCHEMBL492634 | 0.85 | CACNA2D1 (0.38) | TACR1TACR2BDKRB1SLC6A9 | |
| SCHEMBL493578 | 0.84 | NAPEPLD (0.37) | PTGIRBDKRB1 | |
| SCHEMBL493151 | 0.84 | TACR1 (0.37) | TACR1TACR2BDKRB1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | claimed |
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | GRM5 1566/4885TACR1 1774/4885TACR2 3151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.