Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 16/20 | 0.40 |
| ▸ | THRA | P10827 | 15/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717868 | 0.91 | MEN1 (0.36) | THRBTHRAMEN1ALDH1A1ABL1 | |
| SCHEMBL4932217 | 0.91 | THRB (0.48) | THRBTHRA | |
| SCHEMBL4929648 | 0.91 | THRB (0.41) | THRBTHRA | |
| SCHEMBL4929682 | 0.91 | THRB (0.41) | THRBTHRAMEN1KMT2A | |
| SCHEMBL4924452 | 0.90 | THRA (0.39) | THRBTHRA | |
| SCHEMBL5115648 | 0.85 | THRB (0.53) | THRBTHRAMEN1ALDH1A1KMT2A | |
| SCHEMBL4926650 | 0.85 | THRB (0.40) | THRBTHRAMEN1MAPTKMT2A | |
| SCHEMBL4929450 | 0.85 | THRB (0.41) | THRBTHRAMRGPRX4MEN1KMT2A | |
| SCHEMBL4931801 | 0.84 | ALDH1A1 (0.39) | MRGPRX4MEN1ALDH1A1ABL1LMNA | |
| SCHEMBL5717755 | 0.84 | THRA (0.37) | THRBTHRAMEN1ALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | THRB 4/4885THRA 3/4885MRGPRX4 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.