SCHEMBL4928440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5717901	0.95	GPR139 (0.36)	GPR139HSD17B10ALDH1A1GAAKDM4E
	SCHEMBL5105172	0.89	BRD4 (0.39)	GPR139ALDH1A1GAAKDM4EMEN1
	SCHEMBL4930828	0.89	SMN1; SMN2 (0.39)	GPR139MEN1RAB9AKMT2ALMNA
	SCHEMBL4934497	0.89	HSD17B10 (0.39)	GPR139HSD17B10ALDH1A1GAAKDM4E
	SCHEMBL4932562	0.89	ALDH1A1 (0.39)	GPR139HSD17B10ALDH1A1GAAKDM4E
	SCHEMBL5110128	0.89	SENP5 (0.40)	GPR139HSD17B10ALDH1A1GAAKDM4E
	SCHEMBL4924012	0.88	HSD17B10 (0.38)	HSD17B10ALDH1A1GAAKDM4EMEN1
	SCHEMBL5717927	0.87	THRA (0.45)	—
	SCHEMBL4931811	0.87	THRA (0.40)	HSD17B10ALDH1A1GAAKDM4EMEN1
	SCHEMBL4923555	0.87	MRGPRX4 (0.41)	MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.