Pivalate

Pivalate

SCHEMBL4928477

CC(C)(C)C(=O)O.CCC[N+](C)(CCC)CCC

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
FFAR3 O14843 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
BBOX1 O75936 2/20 0.31
SLC22A1 O15245 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tributylmethylammonium SCHEMBL4924826 0.86 BBOX1 (0.38) TSHRALDH1A1BBOX1SLC22A1
Pivalate SCHEMBL4928417 0.85 ACHE (0.36) TSHRALDH1A1CYP2D6CYP2C19HIF1A
Pivalate SCHEMBL5575015 0.84 DNM1 (0.41) TSHRALDH1A1SLC22A1
Pivalate SCHEMBL4928472 0.83 BBOX1 (0.39) TSHRFFAR3HDAC3HDAC1HDAC2
Pivalate SCHEMBL5571705 0.82 DNM1 (0.44) TSHRALDH1A1SLC22A1
Pivalate SCHEMBL5574163 0.82 DNM1 (0.44) TSHRALDH1A1SLC22A1
Pivalate SCHEMBL5571684 0.82 DNM1 (0.44) TSHRALDH1A1SLC22A1
Pivalate SCHEMBL5570490 0.82 DNM1 (0.44) TSHRALDH1A1SLC22A1
Tetrapropylammonium SCHEMBL2353672 0.82 SLC22A1 (0.53) TSHRALDH1A1CYP2D6CYP2C19HIF1A
Oxalic Acid SCHEMBL1050655 0.81 ALOX15 (0.37) TSHRALDH1A1FFAR3HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080312351-A1 Tetraalkylammonium Carboxylate Salts as Trimerization Catalysts for Spray Foam Applications AIR PRODUCTS AND CHEMICALS, INC. (US) 2008-12-18 US claimed
EP-2003157-A2 Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications Air Products and Chemicals, Inc. (US) 2008-12-17 EP claimed
US-20080312351-A1 Tetraalkylammonium Carboxylate Salts as Trimerization Catalysts for Spray Foam Applications AIR PRODUCTS AND CHEMICALS, INC. (US) 2008-12-18 US disclosed
EP-2003157-A2 Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications Air Products and Chemicals, Inc. (US) 2008-12-17 EP disclosed