SCHEMBL4928550

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6466794	0.89	ALDH1A1 (0.86)	ALDH1A1MAPTSMN1; SMN2FBP1LMNA
	SCHEMBL8291630	0.85	ALDH1A1 (0.70)	ALDH1A1MAPTSMN1; SMN2FBP1LMNA
	SCHEMBL4919256	0.84	HDAC6 (0.76)	ALDH1A1MAPTLMNATP53HDAC6
	SCHEMBL5186630	0.82	ALDH1A1 (0.75)	ALDH1A1MAPTSMN1; SMN2FBP1LMNA
	SCHEMBL23447451	0.82	ALDH1A1 (0.74)	ALDH1A1MAPTSMN1; SMN2FBP1LMNA
	SCHEMBL8375828	0.79	PTGS2 (0.66)	ALDH1A1LMNATP53CA1CA2
	SCHEMBL14260712	0.79	MAPT (0.56)	ALDH1A1MAPTSMN1; SMN2FBP1LMNA
	SCHEMBL9176266	0.79	PTGS2 (0.78)	ALDH1A1TP53HDAC6CA1CA2
	SCHEMBL6467568	0.79	FBP1 (0.78)	ALDH1A1MAPTSMN1; SMN2FBP1LMNA
	SCHEMBL19358853	0.79	TP53 (0.81)	ALDH1A1MAPTLMNATP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.