SCHEMBL4929005

SCHEMBL4929005

CC(O)COC(C)C(O)(N=C=O)N=C=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482801 0.73 MAPK1 (0.48) MAPK1TDP1
SCHEMBL10604376 0.71
SCHEMBL11786191 0.67 MAPK1 (0.41) MAPK1TDP1
SCHEMBL11856532 0.67 TDP1 (0.34) MAPK1TDP1
SCHEMBL6129172 0.66 TDP1 (0.41) MAPK1TDP1
SCHEMBL10939225 0.62 TDP1 (0.42) TDP1
SCHEMBL1759721 0.62 TDP1 (0.46) MAPK1TDP1
SCHEMBL1190952 0.61
SCHEMBL28817469 0.60 LMNA (0.31)
SCHEMBL1416856 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118526463-B Special controlled release oral preparation based on compound lactose and preparation method thereof 上海华茂药业有限公司 2025-04-11 CN claimed
CN-118526463-A Special controlled release oral preparation based on compound lactose and preparation method thereof 上海华茂药业有限公司 2024-08-23 CN claimed
EP-4010311-B1 POLYISOCYANATE AND PROCESS FOR PREPARING THE SAME COVESTRO DEUTSCHLAND AG (DE) 2025-09-03 EP disclosed
EP-3953405-B1 PROCESS FOR THE PREPARATION OF POLYISOCYANATES WITH DIMER, TRIMER AND/OR ALLOPHANATE AND OPTIONALLY URETHANE STRUCTURE COVESTRO DEUTSCHLAND AG (DE) 2025-08-06 EP disclosed
CN-118526463-B Special controlled release oral preparation based on compound lactose and preparation method thereof 上海华茂药业有限公司 2025-04-11 CN disclosed
CN-119212803-A Method for producing multilayer coating film 日涂工业涂料有限公司 2024-12-27 CN disclosed
CN-118526463-A Special controlled release oral preparation based on compound lactose and preparation method thereof 上海华茂药业有限公司 2024-08-23 CN disclosed
WO-2024142549-A1 METHOD FOR PRODUCING MULTILAYER COATING FILM 日本ペイント・インダストリアルコーティングス株式会社 2024-07-04 WO disclosed
WO-2024142551-A1 METHOD FOR PRODUCING MULTILAYER COATING FILM 日本ペイント・インダストリアルコーティングス株式会社 2024-07-04 WO disclosed
WO-2024142550-A1 COATING COMPOSITION 日本ペイント・インダストリアルコーティングス株式会社 2024-07-04 WO disclosed
CN-118253464-A Method for producing multilayer coating film 日涂工业涂料有限公司 2024-06-28 CN disclosed
US-6992186-B2 Process for preparing low-monomer-content TDI trimers BAYER AKTIENGESELLSCHAFT (DE) 2006-01-31 US disclosed
US-6936678-B2 Process for preparing low-monomer-content TDI trimers BAYER AKTIENGESELLSCHAFT (DE) 2005-08-30 US disclosed
US-20050154227-A1 solvent free; thermal cleavage of carbamic esters into the isocyanate and alcohol; cleavage gases are cooled and condensed using a liquid coolant (which is the product alcohol) before carrying out rectification; hexamethylenedi-n-butylurethane to hexamethylene diisocyante and butanol BASF AKTIENGESELLSCHAFT (DE) 2005-07-14 US disclosed
US-20040024213-A1 Process for preparing low-monomer-content TDI trimers COVESTRO DEUTSCHLAND AG (DE) 2004-02-05 US disclosed
US-20040006228-A1 Process for preparing low-monomer-content TDI trimers COVESTRO DEUTSCHLAND AG (DE) 2004-01-08 US disclosed
US-6664415-B2 Process for preparing organic monoisocyanates BAYER AKTIENGESELLSCHAFT (DE) 2003-12-16 US disclosed
US-6395925-B1 ADDING AN ALCOHOL OR MERCAPTAN TO AN ISOCYANATE, HEATING AND STRIPPING, DISTILLATION AND PURIFICATION BAYER AKTIENGESELLSCHAFT (DE) 2002-05-28 US disclosed
US-6391161-B1 DECHLORINATION OF ISOCYANATES PURIFYING ORGANIC ISOCYANATES OR MIXTURES OF ISOCYANATES BY REDUCING THE CONTENT OF CHLORINE COMPOUNDS. BAYER AKTIENGESELLSCHAFT (DE) 2002-05-21 US disclosed
US-6222066-B1 CONTACTING ISOCYANATE IN WHICH CHLORINE IS PRESENT WITH GEL-TYPE OR MACROPOROUS ANION-EXCHANGING ORGANIC MATERIAL CONTAINING TERTIARY AND/OR QUATERNARY AMINO GROUPS WHICH IS FREE OF METAL IONS, WATER AND SOLVENT TO PURIFY BAYER AKTIENGESELLSCHAFT (DE) 2001-04-24 US disclosed