Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.40 |
| ▸ | THRB | P10828 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922907 | 0.93 | THRA (0.38) | THRATHRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4932888 | 0.92 | SMN1; SMN2 (0.39) | THRATHRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4934497 | 0.90 | HSD17B10 (0.39) | SMN1; SMN2MEN1KMT2AGPR139LMNA | |
| SCHEMBL4525410 | 0.89 | THRA (0.40) | THRATHRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4351934 | 0.89 | THRA (0.42) | THRATHRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4931530 | 0.89 | SMN1; SMN2 (0.43) | THRATHRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5110890 | 0.89 | SENP5 (0.40) | THRATHRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4930828 | 0.88 | SMN1; SMN2 (0.39) | THRATHRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4354050 | 0.87 | THRB (0.50) | THRATHRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4523210 | 0.86 | SMN1; SMN2 (0.40) | THRATHRBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | THRA 3/4885THRB 4/4885SMN1; SMN2 4282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.