Tributyrin

Tributyrin

SCHEMBL4930164

CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC.OCC(O)CO

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.60
ALDH1A1 P00352 1/20 0.60
PRKCA P17252 4/20 0.59
PRKCE Q02156 2/20 0.59
PRKCQ Q04759 2/20 0.59
PRKCD Q05655 2/20 0.59
KDM4E B2RXH2 1/20 0.54
DUSP3 P51452 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
LPAR3 Q9UBY5 4/20 0.49
LPAR1 Q92633 2/20 0.49
ENPP2 Q13822 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
SELP P16109 1/20 0.48
LPAR2 Q9HBW0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tributyrin SCHEMBL14638861 0.95 LMNA (0.55) LMNAALDH1A1PRKCAPRKCEPRKCQ
Tributyrin SCHEMBL27449158 0.90 ALDH1A1 (0.60) LMNAALDH1A1PRKCAPRKCEPRKCQ
Tributyrin SCHEMBL11903346 0.89 LMNA (0.55) LMNAALDH1A1PRKCAPRKCEPRKCQ
Tributyrin SCHEMBL28601109 0.89 ALDH1A1 (0.68) LMNAALDH1A1PRKCAPRKCEPRKCQ
Tributyrin SCHEMBL601928 0.89 ALDH1A1 (0.72) LMNAALDH1A1PRKCAPRKCEPRKCQ
Tributyrin SCHEMBL23825 0.89 ALDH1A1 (0.72) LMNAALDH1A1PRKCAPRKCEPRKCQ
Tributyrin SCHEMBL9694317 0.87 ALDH1A1 (0.66) LMNAALDH1A1PRKCAPRKCEPRKCQ
SCHEMBL2927505 0.87 PRKCA (0.75) LMNAALDH1A1PRKCAPRKCEPRKCQ
SCHEMBL77143 0.87 PRKCA (0.75) LMNAALDH1A1PRKCAPRKCEPRKCQ
Tripalmitin SCHEMBL16653055 0.87 LMNA (0.82) LMNAALDH1A1PRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527233-A Method for continuously producing succinic anhydride 上海师范大学 2021-10-22 CN claimed
US-9046524-B1 Method to quantify and measure excess colipase in a pancreatin active pharmaceutical ingredient SCIENTIFIC PROTEIN LABORATORIES, LLC (US) 2015-06-02 US claimed
US-5462983-A Biodegradable moldable products and films comprising blends of starch esters and polyesters EVERCORN, INC. (US) 1995-10-31 US claimed
CN-119113989-A Preparation device and method of glycerol tributyrate 山东成武易信环保科技有限公司 2024-12-13 CN disclosed
US-20240124383-A1 METHODS FOR PRODUCTION OF AN ESTER OF BUTYRIC ACID SUPERBREWED FOOD INC (US) 2024-04-18 US disclosed
EP-3210997-B1 AGENTS AND METHODS FOR THE EXPRESSION AND SECRETION OF PEPTIDES AND PROTEINS NUMAFERM GMBH (DE) 2023-07-26 EP disclosed
WO-2022175797-A1 METHODS FOR PRODUCTION OF AN ESTER OF BUTYRIC ACID SUPERBREWED FOOD, INC. (US) 2022-08-25 WO disclosed
EP-2768848-B1 AGENTS AND METHODS FOR THE EXPRESSION AND SECRETION OF PEPTIDES AND PROTEINS NUMAFERM GMBH (DE) 2018-07-04 EP disclosed
CN-107652180-A The production method of tributyrin 天津晶林新材料科技有限公司 2018-02-02 CN disclosed
EP-3210997-A1 AGENTS AND METHODS FOR THE EXPRESSION AND SECRETION OF PEPTIDES AND PROTEINS Heinrich-Heine-Universität Düsseldorf (DE) 2017-08-30 EP disclosed
US-9493804-B2 Agents and methods for the expression and secretion of peptides and proteins HEINRICH-HEINE-UNIVERSITAET DUESSELDORF (DE) 2016-11-15 US disclosed
EP-1408933-A2 SILDENAFIL CITRATE CHEWING GUM FORMULATIONS AND METHODS OF USING THE SAME WM. WRIGLEY JR. COMPANY (US) 2004-04-21 EP disclosed
US-6592850-B2 Sildenafil citrate chewing gum formulations and methods of using the same WM. WRIGLEY JR. COMPANY 2003-07-15 US disclosed
US-6531114-B1 Sildenafil citrate chewing gum formulations and methods of using the same WM. WRIGLEY JR. COMPANY 2003-03-11 US disclosed
WO-2002041840-A2 SILDENAFIL CITRATE CHEWING GUM FORMULATIONS AND METHODS OF USING THE SAME WM. WRIGLEY JR. COMPANY (US) 2002-05-30 WO disclosed
US-20020012633-A1 Sildenafil citrate chewing gum formulations and methods of using the same GMUNDER CHARLEAN B (US) 2002-01-31 US disclosed
EP-0706578-B1 PROCESS FOR THE ESTERIFICATION OF CARBOXYLIC ACIDS WITH TERTIARY ALCOHOLS UNICHEMA CHEMIE BV (NL) 1998-09-09 EP disclosed
US-5658769-A Process for the esterification of carboxylic acids with tertiary alcohols using a lipase from Candida antarctica UNICHEM CHEMIE BV (NL) 1997-08-19 US disclosed
EP-0706578-A1 PROCESS FOR THE ESTERIFICATION OF CARBOXYLIC ACIDS WITH TERTIARY ALCOHOLS UNICHEMA CHEMIE B.V. (NL) 1996-04-17 EP disclosed
WO-1995001450-A1 PROCESS FOR THE ESTERIFICATION OF CARBOXYLIC ACIDS WITH TERTIARY ALCOHOLS UNICHEMA CHEMIE B.V. (NL) 1995-01-12 WO disclosed