Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 9/20 | 0.48 |
| ▸ | CA2 | P00918 | 9/20 | 0.48 |
| ▸ | CA9 | Q16790 | 8/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL27580187 | 1.00 | USP2 (0.53) | USP2CA1CA2CA9CA12 | |
| Glycerin SCHEMBL9437228 | 0.94 | USP2 (0.51) | USP2CA1CA2CA9CA12 | |
| SCHEMBL28122486 | 0.92 | USP2 (0.49) | USP2CA1CA2CA9CA12 | |
| Oleyl Sulfate SCHEMBL27559741 | 0.91 | DGKA (0.51) | USP2 | |
| Glycerin SCHEMBL8525425 | 0.89 | USP2 (0.44) | USP2CA1CA2CA9CA12 | |
| Propylene Glycol SCHEMBL28259413 | 0.89 | CA1 (0.48) | USP2CA1CA2CA9CA12 | |
| SCHEMBL1852790 | 0.88 | CA1 (0.52) | USP2CA1CA2CA9CA12 | |
| Isopropyl Alcohol SCHEMBL9403961 | 0.87 | CA1 (0.53) | USP2CA1CA2CA9CA12 | |
| Alcohol SCHEMBL3995143 | 0.87 | CA1 (0.57) | CA1CA2CA9CA12CA7 | |
| Alcohol SCHEMBL11428503 | 0.87 | CA1 (0.57) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710231-A | Meloxicam eutectic composition | 麦兰专业有限合伙公司 | 2021-11-26 | — | — | CN | disclosed |
| US-20120213996-A1 | ALLERGEN-INHIBITING FIBERS | SUZUKI TARO (JP) | 2012-08-23 | — | — | US | disclosed |
| US-20080138311-A1 | Allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet | SUZUKI TARO | 2008-06-12 | — | — | US | disclosed |
| US-20050095222-A1 | Allergen inhibitor, allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet | SEKISUI CHEMICAL CO., LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| WO-1988008304-A1 | PHARMACEUTICAL COMPOSITION | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1988-11-03 | — | — | WO | disclosed |
| US-4022880-A | ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS | LEVER BROTHERS COMPANY (US) | 1977-05-10 | — | — | US | disclosed |
| US-4011309-A | CITRIC ACID, SODIUM CITRATE, NONIONIC SURFACTANT | MARION LABORATORIES, INC. (US) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050095222-A1 | Allergen inhibitor, allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet | CMA1, HLA-DRB1, ITCH | USP2 1060/4885CA1 216/4885CA2 36/4885 |
| US-20080138311-A1 | Allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet | CMA1, HRH2, HLA-DRB1 | USP2 907/4885CA1 194/4885CA2 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.