Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | THRA | P10827 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717979 | 0.95 | THRA (0.38) | THRBTHRAALDH1A1GRM4FAAH | |
| SCHEMBL4926964 | 0.90 | ALDH1A1 (0.39) | THRBTHRAALDH1A1FAAHBCHE | |
| SCHEMBL4934553 | 0.90 | GRM4 (0.38) | THRBTHRAALDH1A1GRM4L3MBTL1 | |
| SCHEMBL5717789 | 0.89 | THRA (0.40) | THRBTHRAALDH1A1CRHR1 | |
| SCHEMBL4926394 | 0.89 | DHODH (0.40) | THRBTHRAALDH1A1GRM4FABP4 | |
| SCHEMBL5718067 | 0.88 | THRA (0.37) | THRBTHRAALDH1A1GRM4MAPT | |
| SCHEMBL5717987 | 0.87 | FAAH (0.35) | THRBTHRAALDH1A1GRM4FAAH | |
| SCHEMBL4931336 | 0.86 | ALDH1A1 (0.44) | THRBTHRAALDH1A1MRGPRX4L3MBTL1 | |
| SCHEMBL4929575 | 0.85 | LMNA (0.40) | THRBTHRAALDH1A1CRHR1 | |
| SCHEMBL4930968 | 0.84 | ALDH1A1 (0.42) | THRBTHRAALDH1A1GRM4MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | THRB 4/4885THRA 3/4885ALDH1A1 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.