Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550780 | 0.83 | TNKS (0.51) | ALDH1A1HPGDMAPTSMN1; SMN2KMT2A | |
| SCHEMBL17437483 | 0.81 | PDE7A (0.53) | ALDH1A1HPGDMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4932698 | 0.77 | HPGD (0.73) | ALDH1A1HPGDMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4924906 | 0.75 | PKM (0.69) | ALDH1A1HPGDMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4928393 | 0.75 | ALDH1A1 (0.66) | ALDH1A1HPGDMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4930256 | 0.75 | MAPT (0.66) | ALDH1A1HPGDMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4931641 | 0.73 | ALDH1A1 (0.63) | ALDH1A1HPGDMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4934253 | 0.73 | HPGD (0.63) | ALDH1A1HPGDMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4921699 | 0.72 | MAPT (0.66) | ALDH1A1HPGDMAPTSMN1; SMN2KMT2A | |
| SCHEMBL540452 | 0.71 | DRD1 (0.58) | ALDH1A1HPGDSMN1; SMN2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021069-A1 | Receptor Function Regulating Agent | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | US | disclosed |
| EP-1810677-A1 | RECEPTOR FUNCTION REGULATING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2007-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021069-A1 | Receptor Function Regulating Agent | GPR119, INSR, GPR65 | ALDH1A1 1870/4885HPGD 1922/4885MAPT 4574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.