Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933205 | 1.00 | ATG4B (0.56) | ATG4BPLA2G1BMAPTTHRBALDH1A1 | |
| SCHEMBL801295 | 0.82 | MAPT (0.62) | MAPTALDH1A1LMNAHPGDHTT | |
| SCHEMBL10958212 | 0.81 | THRB (0.58) | MAPTTHRBALDH1A1LMNATHRA | |
| SCHEMBL7405689 | 0.81 | CYP4Z1 (0.55) | MAPTTHRBALDH1A1LMNAHPGD | |
| SCHEMBL7405692 | 0.81 | CYP4Z1 (0.55) | MAPTTHRBALDH1A1LMNAHPGD | |
| SCHEMBL6393097 | 0.80 | ALDH1A1 (0.57) | MAPTTHRBALDH1A1LMNATDP1 | |
| SCHEMBL68851 | 0.80 | CYP4Z1 (0.62) | MAPTALDH1A1LMNACYP4Z1KMT2A | |
| SCHEMBL14066833 | 0.79 | ATG4B (0.68) | ATG4BPLA2G1BMAPTTHRBALDH1A1 | |
| SCHEMBL16226978 | 0.79 | ATG4B (0.68) | ATG4BPLA2G1BMAPTTHRBALDH1A1 | |
| SCHEMBL1686769 | 0.78 | LMNA (0.52) | MAPTALDH1A1LMNAHTTCYP4Z1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227770-A1 | Benzoxazepine Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-18 | — | — | US | disclosed |
| EP-1650201-A1 | BENZOXAZEPINE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227770-A1 | Benzoxazepine Compound | NR1H2, SQLE, NR1H3 | ATG4B 4291/4885PLA2G1B 1166/4885MAPT 4191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.