Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 9/20 | 0.40 |
| ▸ | THRB | P10828 | 9/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933408 | 0.92 | FABP4 (0.42) | FABP4FABP5THRATHRBMRGPRX4 | |
| SCHEMBL5717866 | 0.91 | HPGD (0.40) | FABP4FABP5THRATHRBMRGPRX4 | |
| SCHEMBL4928683 | 0.90 | THRA (0.46) | THRATHRBMRGPRX4 | |
| SCHEMBL4933354 | 0.90 | THRB (0.49) | THRATHRBMEN1ALDH1A1LMNA | |
| SCHEMBL4929364 | 0.89 | FABP4 (0.42) | FABP4FABP5THRATHRBMEN1 | |
| SCHEMBL4922999 | 0.87 | MRGPRX4 (0.46) | FABP4FABP5THRATHRBMRGPRX4 | |
| SCHEMBL4933925 | 0.86 | THRB (0.39) | THRATHRBMEN1KMT2A | |
| SCHEMBL5118962 | 0.85 | THRA (0.53) | FABP4FABP5THRATHRBMRGPRX4 | |
| SCHEMBL4933156 | 0.85 | THRB (0.39) | THRATHRB | |
| SCHEMBL5108841 | 0.85 | FABP4 (0.42) | FABP4FABP5THRATHRBMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | FABP4 1747/4885FABP5 1863/4885THRA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.