Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 16/20 | 0.39 |
| ▸ | THRA | P10827 | 15/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922939 | 0.92 | THRB (0.40) | THRBTHRAPTGS2ABCB11PTGS1 | |
| SCHEMBL5718235 | 0.91 | ALDH1A1 (0.34) | THRBTHRAS1PR2S1PR1S1PR3 | |
| SCHEMBL4933925 | 0.91 | THRB (0.39) | THRBTHRAS1PR2S1PR1S1PR3 | |
| SCHEMBL4934279 | 0.90 | FFAR4 (0.41) | THRBTHRA | |
| SCHEMBL4931497 | 0.90 | THRB (0.49) | THRBTHRAPPARG | |
| SCHEMBL4926366 | 0.87 | THRB (0.41) | THRBTHRAPTGS2ABCB11PTGS1 | |
| SCHEMBL5112221 | 0.85 | THRB (0.53) | THRBTHRAPTGS2ABCB11PTGS1 | |
| SCHEMBL4933489 | 0.85 | FABP4 (0.41) | THRBTHRA | |
| SCHEMBL5108039 | 0.85 | THRB (0.41) | THRBTHRAPTGS2ABCB11PTGS1 | |
| SCHEMBL4930388 | 0.84 | THRB (0.43) | THRBTHRAPTGS2ABCB11PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | THRB 4/4885THRA 3/4885PTGS2 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.