Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403545 | 0.82 | POLB (0.61) | POLBCES2CES1AKR1B1ALDH1A1 | |
| SCHEMBL9264805 | 0.80 | — | — | |
| SCHEMBL238714 | 0.78 | AKR1B1 (0.61) | POLBCES2CES1AKR1B1ALDH1A1 | |
| SCHEMBL5346138 | 0.77 | ALDH1A1 (0.63) | ALDH1A1KMT2AHSD17B10CYP3A4 | |
| SCHEMBL1570263 | 0.77 | LMNA (0.44) | POLBALDH1A1KMT2AHPGDHTT | |
| SCHEMBL28249833 | 0.77 | L3MBTL1 (0.46) | POLBALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL483034 | 0.76 | — | — | |
| SCHEMBL21381425 | 0.76 | CES1 (0.36) | CES2CES1AKR1B1ALDH1A1CA2 | |
| Water SCHEMBL28157653 | 0.76 | CTBP2 (0.52) | POLBALDH1A1KMT2AHPGDCYP2C19 | |
| SCHEMBL828463 | 0.76 | CA2 (0.58) | CES2CES1AKR1B1ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209449-B | Inhibitors of the kynurenine pathway | 库拉德夫制药私人有限公司 | 2019-02-01 | — | — | CN | claimed |
| CN-102653543-A | Preparation method, biological activity and application of 3-substituted type Jolkinolide compound | UNIV CHINA PHARMA | 2012-09-05 | — | — | CN | claimed |
| CN-110635053-B | P-type doped material, hole injection material containing same, hole injection layer and OLED display panel | 上海和辉光电股份有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-110635053-A | P-type doped material, hole injection material containing same, hole injection layer and OLED display panel | 上海和辉光电有限公司 | 2019-12-31 | — | — | CN | disclosed |
| CN-105517949-B | Mixed semiconductor's polymer nano granules as Polarization-Sensitive fluorescence probe | 华盛顿大学商业中心 | 2019-11-12 | — | — | CN | disclosed |
| CN-106029649-B | Ethynyl derivatives | 豪夫迈·罗氏有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-106170479-B | Acetenyl-imidazolidine-2,4-dione derivative as MGLUR4 regulator | 豪夫迈·罗氏有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-105209449-B | Inhibitors of the kynurenine pathway | 库拉德夫制药私人有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-104487097-B | Chromophoric polymer dots with narrow-band emission | 华盛顿大学商业中心 | 2019-01-18 | — | — | CN | disclosed |
| CN-105579447-B | Ethynyl derivatives serving | 豪夫迈·罗氏有限公司 | 2018-11-13 | — | — | CN | disclosed |
| CN-105263855-B | The system and method analyzed using polymer point | 华盛顿大学商业中心 | 2018-09-18 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| CN-1349497-A | Monofluoroalkyl derivatives | LILLY CO ELI (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1070863-C | Phosphonic diester derivatives | OTSUKA PHARMA CO LTD (JP) | 2001-09-12 | — | — | CN | disclosed |
| US-6262205-B1 | CURING RADICAL-POLYMERIZABLE MULTICOMPONENT MIXTURE CONTAINING OLEFINICALLY-UNSATURATED COMPOUND WITH AIR BY ADDING TO ALKYL, CYCLOALKYL OR ARYL HYDRAZONE OF AN ALIPHATIC, CYCLOALIPHATIC OR AROMATIC ALDEHYDE OR KETONE AND METAL COMPOUND | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-07-17 | — | — | US | disclosed |
| CN-1206419-A | Phosphonic acid diester derivatives | OTSUKA PHARMA CO LTD (JP) | 1999-01-27 | — | — | CN | disclosed |
| EP-0236624-B1 | SUBSTITUTED PHENYL ETHANOL AMINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1993-08-11 | — | — | EP | disclosed |
| WO-1983004024-A1 | 2(1H)-PYRIDONE DERIVATIVES, PREPARATION THEREOF AND COMPOSITION CONTAINING THEM | SANDOZ AG (CH) | 1983-11-24 | — | — | WO | disclosed |
| US-4119652-A | HYDROGENATION CATALYSTS; COORDINATION COMPOUNDS OF IRIDIUM, RHODIUM OR RUTHENIUM WITH PHOSPHINE OR ARSINE LIGANDS; OPTICALLY ACTIVE | MONSANTO COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-3972878-A | Method for preparing azines and hydrazones | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-08-03 | — | — | US | disclosed |