Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.32 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.32 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717783 | 0.95 | PTGDR (0.34) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL4924159 | 0.92 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL4922902 | 0.91 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL4929630 | 0.88 | SUCNR1 (0.39) | PDE4APDE4BPDE4CPDE4DUSP5 | |
| SCHEMBL5717790 | 0.87 | KMT2A (0.32) | HSD17B10MEN1GAAMAPTKMT2A | |
| SCHEMBL5718149 | 0.86 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL4927388 | 0.85 | GPR139 (0.38) | HSD17B10MEN1ALDH1A1ABL1LMNA | |
| SCHEMBL4932686 | 0.84 | THRB (0.37) | MEN1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL4931803 | 0.84 | ALDH1A1 (0.38) | HSD17B10MEN1ALDH1A1ABL1LMNA | |
| SCHEMBL5718084 | 0.83 | SUCNR1 (0.39) | PDE4APDE4BPDE4CPDE4DMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | PDE4A 897/4885PDE4B 1391/4885PDE4C 1556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.