Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4269263 | 0.88 | TSHR (0.61) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL1205031 | 0.86 | CYP1A2 (0.71) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL4940669 | 0.86 | ALDH1A1 (0.86) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL374443 | 0.82 | CYP1A2 (0.85) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL4941593 | 0.80 | CRHBP (0.50) | ALDH1A1LMNATSHRCYP1A2CYP2C9 | |
| SCHEMBL365344 | 0.80 | TSHR (0.73) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL8421360 | 0.79 | ALDH1A1 (0.68) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL189560 | 0.79 | TSHR (0.67) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL356063 | 0.79 | TSHR (1.00) | ALDH1A1LMNATSHRCYP1A2CYP2D6 | |
| SCHEMBL30833623 | 0.79 | TSHR (0.67) | ALDH1A1LMNATSHRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | ACADEMIA SINICA (TW) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | BCL9, MCL1, BCL9L | ALDH1A1 1237/4885LMNA 2555/4885TSHR 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.