SCHEMBL4935843

SCHEMBL4935843

C=CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC=C)C1c1ccc(C)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.82
ALDH1A1 P00352 6/20 0.82
HSD17B10 Q99714 3/20 0.82
HPGD P15428 2/20 0.82
TP53 P04637 2/20 0.82
MAPT P10636 6/20 0.63
MEN1 O00255 5/20 0.62
KMT2A Q03164 5/20 0.62
POLB P06746 1/20 0.62
NPSR1 Q6W5P4 2/20 0.60
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2D6 P10635 1/20 0.60
CYP2C9 P11712 1/20 0.60
CYP2C19 P33261 1/20 0.60
LMNA P02545 4/20 0.58
GAA P10253 2/20 0.58
MAPK1 P28482 1/20 0.58
TSHR P16473 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3027621 0.89 KDM4E (0.79) KDM4EALDH1A1HSD17B10HPGDTP53
SCHEMBL10475395 0.89 ALDH1A1 (0.78) KDM4EALDH1A1HSD17B10HPGDTP53
SCHEMBL10475396 0.85 CACNA1B (0.74) KDM4EALDH1A1HSD17B10HPGDTP53
SCHEMBL9064752 0.84 ADORA3 (0.74) KDM4EALDH1A1HSD17B10HPGDTP53
SCHEMBL3032293 0.84 KDM4E (0.80) KDM4EALDH1A1HSD17B10HPGDTP53
SCHEMBL24469031 0.82 ALDH1A1 (0.68) KDM4EALDH1A1HSD17B10HPGDTP53
SCHEMBL9505249 0.81 ALDH1A1 (0.67) KDM4EALDH1A1HSD17B10HPGDTP53
SCHEMBL10113156 0.81 MEN1 (0.78) KDM4EALDH1A1HSD17B10HPGDTP53
SCHEMBL7267309 0.79 KDM4E (0.72) KDM4EALDH1A1HSD17B10HPGDTP53
SCHEMBL7817206 0.79 KDM4E (0.88) KDM4EALDH1A1HSD17B10HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080308492-A1 Filter Medium for Technical Applications, and Method for the Production Thereof MAHLE INTERNATIONAL GMBH (DE) 2008-12-18 US claimed
US-20080308492-A1 Filter Medium for Technical Applications, and Method for the Production Thereof MAHLE INTERNATIONAL GMBH (DE) 2008-12-18 US disclosed