Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.58 |
| ▸ | MLNR | O43193 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10475395 | 0.93 | ALDH1A1 (0.78) | ALDH1A1KDM4EHSD17B10TP53HPGD | |
| SCHEMBL9064752 | 0.90 | ADORA3 (0.74) | ALDH1A1KDM4EHSD17B10TP53HPGD | |
| SCHEMBL10830852 | 0.90 | ADORA3 (0.72) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL10475396 | 0.89 | CACNA1B (0.74) | ALDH1A1KDM4EHSD17B10TP53HPGD | |
| SCHEMBL23686116 | 0.85 | KMT2A (0.70) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL11862107 | 0.85 | ADORA3 (0.66) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL9505249 | 0.85 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10TP53HPGD | |
| SCHEMBL4935843 | 0.82 | KDM4E (0.82) | ALDH1A1KDM4EHSD17B10TP53HPGD | |
| SCHEMBL4624081 | 0.81 | TP53 (0.62) | ALDH1A1KDM4EHSD17B10TP53HPGD | |
| SCHEMBL22747107 | 0.80 | CACNA1B (0.71) | ALDH1A1MEN1KMT2AADORA3CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169613-A1 | Drp1-FILAMIN COMPLEX FORMATION INHIBITORS | Rdiscovery, LLC | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169613-A1 | Drp1-FILAMIN COMPLEX FORMATION INHIBITORS | FIS1, DNM1L, DNM1 | ALDH1A1 4345/4885KDM4E 4592/4885HSD17B10 2713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.