Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | BAX | Q07812 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16890420 | 0.89 | LTA4H (0.58) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL9988281 | 0.81 | LTA4H (0.55) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL10592307 | 0.79 | LTA4H (0.58) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL49366 | 0.77 | LTA4H (0.55) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL17273646 | 0.72 | LTA4H (0.73) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL4016558 | 0.72 | LTA4H (0.50) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL24043217 | 0.69 | KDM4E (0.41) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL4010724 | 0.68 | ALOX15 (0.49) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL28552141 | 0.67 | LTA4H (0.55) | LTA4HTSHRKDM4EGLAMAPT | |
| SCHEMBL6743011 | 0.67 | LTA4H (0.42) | LTA4HTSHRKDM4EGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200144515-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200144515-A1 | POLYCYCLIC AROMATIC COMPOUND | PAH, ALK, AOC2 | LTA4H 4030/4885TSHR 4594/4885KDM4E 1365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.