Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | TXN | P10599 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7226196 | 0.91 | MAPT (0.67) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL6673841 | 0.83 | CA12 (0.57) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL11837292 | 0.81 | NFKB1 (0.78) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL13852882 | 0.79 | POLB (0.61) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL4094573 | 0.77 | NFKB1 (0.61) | NFKB1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL10495571 | 0.77 | CARM1 (0.42) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL8911586 | 0.76 | NPC1 (0.66) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL13654063 | 0.76 | NFKB1 (0.57) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL1391141 | 0.76 | NFKB1 (0.64) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL3500246 | 0.75 | NFKB1 (0.69) | NFKB1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129730-A1 | GENERATION OF COMPOUND LIBRARIES UTILIZING MOLECULAR IMPRINTS INCLUDING A DOUBLE OR ANTI-IDIOTYPIC APPROACH | KLAUS MOSBACH (SE) | 2012-05-24 | — | — | US | disclosed |
| US-20080234141-A1 | GENERATION OF COMPOUND LIBRARIES UTILIZING MOLECULAR IMPRINTS INCLUDING A DOUBLE OR ANTI-IDIOTYPIC APPROACH | KLAUS MOSBACH (SE) | 2008-09-25 | — | — | US | disclosed |
| US-20050042677-A1 | Generation of compound libraries utilizing molecular imprints including a double or anti-idiotypic approach | MOSBACH, KLAUS (SE) | 2005-02-24 | — | — | US | disclosed |