Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.46 |
| ▸ | MMP8 | P22894 | 10/20 | 0.46 |
| ▸ | MMP1 | P03956 | 9/20 | 0.46 |
| ▸ | MMP9 | P14780 | 9/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4942350 | 0.94 | MMP2 (0.42) | MMP2MMP8MMP1MMP9PSMB5 | |
| SCHEMBL4945243 | 0.88 | PSEN1 (0.43) | MMP2MMP8MMP1MMP9 | |
| SCHEMBL4939642 | 0.83 | MMP1 (0.40) | MMP2MMP8MMP1MMP9FFAR2 | |
| SCHEMBL4065583 | 0.81 | ADORA3 (0.46) | MME | |
| SCHEMBL4939621 | 0.81 | FFAR2 (0.38) | MMP2MMP8MMP1MMP9FFAR2 | |
| SCHEMBL2956970 | 0.80 | PSEN1 (0.40) | MMP2MMP8MMP1MMP9ANPEP | |
| SCHEMBL4958532 | 0.79 | MMP1 (0.38) | MMP2MMP8MMP1MMP9PSMB5 | |
| SCHEMBL4942356 | 0.78 | NR3C2 (0.39) | MMP2MMP8MMP1MMP9PSMB5 | |
| SCHEMBL8317260 | 0.78 | MMP1 (0.36) | MMP2MMP8MMP1MMP9FFAR2 | |
| SCHEMBL2954827 | 0.78 | MMP1 (0.36) | MMP2MMP8MMP1MMP9FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633350-A4 | ACYLATED AMINO ACID AMIDYL PYRAZOLES AND RELATED COMPOUNDS | ELAN PHARM INC (US) | 2008-11-26 | — | — | EP | disclosed |
| EP-1633350-A2 | ACYLATED AMINO ACID AMIDYL PYRAZOLES AND RELATED COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2005009344-A2 | ACYLATED AMINO ACID AMIDYL PYRAZOLES AND RELATED COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 2005-02-03 | — | — | WO | disclosed |