Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288936 | 0.88 | MET (0.54) | METFLT3 | |
| SCHEMBL8286892 | 0.88 | MET (0.61) | METFLT3 | |
| Hydrochloric Acid SCHEMBL4773711 | 0.87 | MET (0.60) | METFLT3 | |
| SCHEMBL8288991 | 0.85 | MET (0.65) | METFLT3 | |
| Trifluoroacetic Acid SCHEMBL4776417 | 0.85 | MET (0.56) | METFLT3 | |
| SCHEMBL4769899 | 0.83 | MET (0.53) | METFLT3 | |
| SCHEMBL4822805 | 0.83 | MET (0.67) | METFLT3 | |
| SCHEMBL4822232 | 0.82 | MET (0.77) | METFLT3 | |
| SCHEMBL4813820 | 0.79 | MET (0.75) | METFLT3 | |
| SCHEMBL4769553 | 0.79 | MET (0.61) | METFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249105-A1 | Pyrrolopyridine-Substituted Benzol Derivatives for Treating Cardiovascular Diseases | BAYER HEALTHCARE AG (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249105-A1 | Pyrrolopyridine-Substituted Benzol Derivatives for Treating Cardiovascular Diseases | PHB2, PHB1, TNNT2 | MET 4445/4885FLT3 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.