SCHEMBL4940577

SCHEMBL4940577

OC(Cl)c1cccc(Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.54
PNMT P11086 2/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
NFKB1 P19838 1/20 0.54
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
GLA P06280 1/20 0.52
TSHR P16473 3/20 0.46
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43
KCNH2 Q12809 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
S100B P04271 1/20 0.37
ITGB3 P05106 1/20 0.37
ITGAV P06756 1/20 0.37
CYP2C19 P33261 2/20 0.36
AOC3 Q16853 1/20 0.36
ADRB2 P07550 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19856483 0.83 CYP1A2 (0.56) CYP1A2PNMTCYP3A4CYP2D6NFKB1
SCHEMBL456765 0.80 ADRB2 (0.47) CYP3A4CYP2D6NFKB1ALDH1A1LMNA
SCHEMBL1872442 0.80 CYP1A2 (0.58) CYP1A2PNMTCYP3A4CYP2D6NFKB1
SCHEMBL7546175 0.79 CYP1A2 (0.63) CYP1A2PNMTCYP3A4CYP2D6NFKB1
SCHEMBL8519506 0.78 ADRB2 (0.46) CYP3A4CYP2D6NFKB1ALDH1A1LMNA
SCHEMBL5742922 0.77 CYP2D6 (0.50) CYP1A2PNMTCYP3A4CYP2D6NFKB1
SCHEMBL5617277 0.76 PNMT (0.54) CYP1A2PNMTCYP3A4CYP2D6NFKB1
SCHEMBL5614982 0.76 PNMT (0.54) CYP1A2PNMTCYP3A4CYP2D6NFKB1
SCHEMBL5614873 0.76 PNMT (0.54) CYP1A2PNMTCYP3A4CYP2D6NFKB1
SCHEMBL9409630 0.76 PNMT (0.54) CYP1A2PNMTCYP3A4CYP2D6NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108745222-B Anti-sedimentation type microreactor and synthesis system 华北电力大学 2023-09-01 CN disclosed
US-20080004387-A1 Alkyl benzyl esters of polycarboxylic acids LANXESS DEUTSCHLAND GMBH (DE) 2008-01-03 US disclosed
US-7105500-B2 Process for the antimicrobial treatment of fiber materials CIBA SPECIALTY CHEMICALS CORP. (US) 2006-09-12 US disclosed
US-20050080044-A1 Process for the antimicrobial treatment of fiber materials HUNTSMAN INTERNATIONAL LLC 2005-04-14 US disclosed
EP-1319102-A1 PROCESS FOR THE ANTIMICROBIAL TREATMENT OF FIBER MATERIALS Ciba SC Holding AG (CH) 2003-06-18 EP disclosed
EP-1201229-A1 Concentrated liquid formulations comprising a microbicidally active ingredient Ciba SC Holding AG (CH) 2002-05-02 EP disclosed
WO-2002022941-A1 PROCESS FOR THE ANTIMICROBIAL TREATMENT OF FIBER MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-03-21 WO disclosed
US-6358906-B1 CHLORINATED AND/OR BROMINATED 2-HYDROXYDIPHENYL ETHER DERIVATIVE; ALCOHOL, SULFONATE, CARBOXYLIC ACID AND WATER; HAND SOAP CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-19 US disclosed
US-6346125-B1 TREATING NONWOVEN WITH AQUEOUS COMPOSITION COMPRISING ANTIMICROBIAL HALOGENO-O-HYDROXYDIPHENYL, SOLUBILIZER FOR ANTIMICROBIAL, OPTIONAL COPOLYMER OF MONOMER HAVING AFFINITY TO TEXTILES AND MONOMER HAVING AFFINITY FOR ANTIMICROBIAL CIBA SPECIALTY CHEMICALS CORPORATION 2002-02-12 US disclosed
US-20010055651-A1 PROCESS FOR THE TREATMENT OF TEXTILE MATERIALS WITH AN ANTIMICROBIAL AGENT CIBA SPECIALTY CHEMICALS CORP. 2001-12-27 US disclosed
EP-1141453-A1 INCORPORATION OF ORGANIC ANTI-MICROBIALS INTO FIBRES DURING A FIBRE SPINNING PROCESS Ciba SC Holding AG (CH) 2001-10-10 EP disclosed
WO-2000026447-A1 INCORPORATION OF ORGANIC ANTI-MICROBIALS INTO FIBRES DURING A FIBRE SPINNING PROCESS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-11 WO disclosed
EP-0937812-A2 Process for the treatment of nonwovens with antimicrobial agents Ciba SC Holding AG (CH) 1999-08-25 EP disclosed
EP-0914085-A2 CONCENTRATED LIQUID ACCUMULATIONS COMPRISING A MICROBICIDALLY ACTIVE INGREDIENT Ciba SC Holding AG (CH) 1999-05-12 EP disclosed
EP-0908553-A2 Process for the treatment of textile materials with an antimicrobial agent Ciba SC Holding AG (CH) 1999-04-14 EP disclosed
WO-1997046218-A2 CONCENTRATED LIQUID FORMULATIONS COMPRISING A MICROBICIDALLY ACTIVE INGREDIENT CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-12-11 WO disclosed
EP-0777717-A2 SURFACE-ACTIVE FORMULATIONS Ciba SC Holding AG (CH) 1997-06-11 EP disclosed
WO-1996006153-A2 SURFACE-ACTIVE FORMULATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-02-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080044-A1 Process for the antimicrobial treatment of fiber materials NOD2, AAAS, C9 CYP1A2 3170/4885PNMT 1065/4885CYP3A4 1804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.