Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665466 | 0.80 | TSHR (0.47) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL1872442 | 0.80 | CYP1A2 (0.58) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL15302407 | 0.79 | CYP1A2 (0.63) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5614982 | 0.76 | PNMT (0.54) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL4940577 | 0.76 | CYP1A2 (0.54) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5617277 | 0.76 | PNMT (0.54) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5933878 | 0.76 | PNMT (0.65) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5614873 | 0.76 | PNMT (0.54) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL14910625 | 0.76 | LMNA (0.57) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL11501928 | 0.76 | CYP1A2 (0.65) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187644-B2 | Continuous processing of asphalt formulations | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2015-11-17 | — | — | US | disclosed |
| US-20140275337-A1 | CONTINUOUS PROCESSING OF ASPHALT FORMULATIONS | BUILDING MATERIALS INVESTMENT CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
| EP-0357176-B1 | Production of ultrastructural ceramics | SULLIVAN THOMAS MILTON (US) | 1994-07-06 | — | — | EP | disclosed |
| US-5238669-A | Silicon nitride or silicon carbide | SULLIVAN THOMAS M (US) | 1993-08-24 | — | — | US | disclosed |
| US-4961913-A | POLYMERIZING NITRIDE PRECURSORS UNDER SUPERCRITICAL PRESSURE AND TEMPERATURE | SULLIVAN THOMAS M (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0357176-A2 | Production of ultrastructural ceramics | Sullivan, Thomas Milton (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4405589-A | ALKYL OR ARYL SILICON CHLORIDES, AMMONIA, ROASTING | UBE INDUSTRIES, LTD. (JP) | 1983-09-20 | — | — | US | disclosed |