Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1872442 | 0.80 | CYP1A2 (0.58) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL11501928 | 0.76 | CYP1A2 (0.65) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5617277 | 0.76 | PNMT (0.54) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5933878 | 0.76 | PNMT (0.65) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL5614982 | 0.76 | PNMT (0.54) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL14910625 | 0.76 | LMNA (0.57) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL4940577 | 0.76 | CYP1A2 (0.54) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL9409630 | 0.76 | PNMT (0.54) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL28905220 | 0.74 | IDO1 (0.54) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL11499495 | 0.73 | CYP1A2 (0.56) | PNMTCYP1A2CYP3A4CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288953-B1 | BIS(AMINOPHENYLPHENOL) LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM | UNIVATION TECH LLC (US) | 2021-01-06 | — | — | EP | disclosed |
| US-10696641-B2 | Bis(aminophenylphenol) ligands and transition metal catalysts prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2020-06-30 | — | — | US | disclosed |
| US-10689314-B2 | Methods for preparing bridged bi-aromatic ligands | UNIVATION TECHNOLOGIES, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-10654029-B2 | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2020-05-19 | — | — | US | disclosed |
| EP-3632920-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | Univation Technologies, LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-3286162-B1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | UNIVATION TECH LLC (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-3285923-B1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | UNIVATION TECH LLC (US) | 2019-07-17 | — | — | EP | disclosed |
| US-20190111414-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2019-04-18 | — | — | US | disclosed |
| US-10252967-B2 | Bridged bi-aromatic ligands and transition metal compounds prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2019-04-09 | — | — | US | disclosed |
| US-10239809-B2 | Methods for preparing bridged bi-aromatic ligands | UNIVATION TECHNOLOGIES, LLC (US) | 2019-03-26 | — | — | US | disclosed |
| EP-0993464-B1 | CATALYST FOR THE PRODUCTION OF OLEFIN POLYMERS | UNION CARBIDE CHEM PLASTIC (US) | 2003-04-16 | — | — | EP | disclosed |
| US-20020086960-A1 | Polymerization catalyst system, polymerization process and polymer therefrom | UNIVATION TECHNOLOGIES, LLC | 2002-07-04 | — | — | US | disclosed |
| US-20020065379-A1 | Catalyst for the production of olefin polymers | MURRAY REX EUGENE (US) | 2002-05-30 | — | — | US | disclosed |
| US-6320005-B1 | CYCLIC HETEROATOM-CONTAINING CATALYST PRECURSOR COMPLEXES OF GROUP 3 TO 6 ELEMENTS AND LANTHANIDES; E.G., (N-(2-PYRIDYL)(BENZYL)METHYL(N-2,6-DIISOPROPYLPHENYL)AMINO)ZIR CONIUM TRIBENZYL | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2001-11-20 | — | — | US | disclosed |
| US-6103657-A | Catalyst for the production of olefin polymers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| US-6096676-A | METALLOCENE COORDINATION CATALYSTS BASED ON A GROUP IVB METAL AND AN ACTIVATING COCATALYST; ADDITION POLYMERATION OF OLEFINS, ALPHA-OLEFINS AND DIENES; HOMOGENEITY; KINETICS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0993464-A1 | CATALYST FOR THE PRODUCTION OF OLEFIN POLYMERS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-04-19 | — | — | EP | disclosed |
| EP-0993471-A2 | CATALYST FOR THE PRODUCTION OF OLEFIN POLYMERS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999001460-A1 | CATALYST FOR THE PRODUCTION OF OLEFIN POLYMERS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001481-A2 | CATALYST FOR THE PRODUCTION OF OLEFIN POLYMERS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696641-B2 | Bis(aminophenylphenol) ligands and transition metal catalysts prepared therefrom | WASF2, WEE2, THEM6 | PNMT 171/4885CYP1A2 1065/4885CYP3A4 390/4885 |
| US-10689314-B2 | Methods for preparing bridged bi-aromatic ligands | TYR, AOC2, BICRA | PNMT 347/4885CYP1A2 146/4885CYP3A4 120/4885 |
| US-10654029-B2 | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | WASF2, WEE2, PICALM | PNMT 33/4885CYP1A2 776/4885CYP3A4 554/4885 |
| US-10239809-B2 | Methods for preparing bridged bi-aromatic ligands | AOC1, TYR, DDT | PNMT 826/4885CYP1A2 166/4885CYP3A4 164/4885 |
| US-20190111414-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | WASF2, WEE2, PICALM | PNMT 33/4885CYP1A2 776/4885CYP3A4 554/4885 |
| US-10252967-B2 | Bridged bi-aromatic ligands and transition metal compounds prepared therefrom | WEE2, WEE1, AHR | PNMT 249/4885CYP1A2 644/4885CYP3A4 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.