Water

Water

SCHEMBL49418

O.[Fe+3].[Fe+3].[S-2].[S-2].[S-2]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL1325238 1.00
Water SCHEMBL6471520 0.87
Water SCHEMBL29618032 0.82
SCHEMBL35133 0.82
SCHEMBL10967333 0.67
Water SCHEMBL771806 0.67
Water SCHEMBL6690795 0.67
Water SCHEMBL1550233 0.67
Water SCHEMBL7764322 0.67
SCHEMBL1095315 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732284-B2 Process for determining presence of mesophase in slurry hydrocracking UOP LLC (US) 2017-08-15 US disclosed
US-8709966-B2 Catalyst composition with nanometer crystallites for slurry hydrocracking UOP LLC (US) 2014-04-29 US disclosed
US-8277638-B2 Process for using catalyst with rapid formation of iron sulfide in slurry hydrocracking UOP LLC (US) 2012-10-02 US disclosed
US-20120085680-A1 PROCESS FOR DETERMINING PRESENCE OF MESOPHASE IN SLURRY HYDROCRACKING UOP LLC (US) 2012-04-12 US disclosed
US-8128810-B2 Process for using catalyst with nanometer crystallites in slurry hydrocracking UOP LLC (US) 2012-03-06 US disclosed
US-8123933-B2 Process for using iron oxide and alumina catalyst for slurry hydrocracking UOP LLC (US) 2012-02-28 US disclosed
US-20110308997-A1 PROCESS FOR USING CATALYST WITH RAPID FORMATION OF IRON SULFIDE IN SLURRY HYDROCRACKING UOP LLC (US) 2011-12-22 US disclosed
US-8062505-B2 Process for using iron oxide and alumina catalyst with large particle diameter for slurry hydrocracking UOP LLC (US) 2011-11-22 US disclosed
US-8025793-B2 Process for using catalyst with rapid formation of iron sulfide in slurry hydrocracking UOP LLC (US) 2011-09-27 US disclosed
EP-2291328-A2 CATALYST COMPOSITION WITH NANOMETER CRYSTALLITES FOR SLURRY HYDROCRACKING UOP LLC (US) 2011-03-09 EP disclosed
US-20090321313-A1 Process for Determining Presence of Mesophase in Slurry Hydrocracking LG DISPLAY CO., LTD. (KR) 2009-12-31 US disclosed
US-20090321316-A1 Process for Using Catalyst with Rapid Formation of Iron Sulfide in Slurry Hydrocracking UOP LLC 2009-12-31 US disclosed
US-20090326302-A1 Process for Using Alumina Catalyst in Slurry Hydrocracking THE UNIVERSITY OF ELECTRO-COMMUNICATIONS (JP) 2009-12-31 US disclosed
US-20090326304-A1 Process for Using Catalyst with Nanometer Crystallites in Slurry Hydrocracking UOP LLC 2009-12-31 US disclosed
US-20090326303-A1 Process for Using Iron Oxide and Alumina Catalyst for Slurry Hydrocracking UOP LLC 2009-12-31 US disclosed
US-20090325789-A1 Catalyst Composition with Nanometer Crystallites for Slurry Hydrocracking UOP LLC 2009-12-31 US disclosed
US-20090321314-A1 Process for Using Iron Oxide and Alumina Catalyst with Large Particle Diameter for Slurry Hydrocracking UOP LLC 2009-12-31 US disclosed
US-20090321315-A1 Process for Using Hydrated Iron Oxide and Alumina Catalyst for Slurry Hydrocracking UOP LLC 2009-12-31 US disclosed
US-7198661-B2 Gas purification medium for removing sulfides from gaseous streams CCR TECHNOLOGIES LTD. (CA) 2007-04-03 US disclosed
US-20050020441-A1 Gas purification medium for removing sulfides from gaseous streams CCR TECHNOLOGIES LTD. (CA) 2005-01-27 US disclosed