SCHEMBL4943666

SCHEMBL4943666

COc1ccc(F)cc1C(C)(C)CC(O)(CNc1ccc2c(c1)COC2=O)Cc1ccc(F)c(F)c1

nearest known ligand 0.84

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 20/20 0.84
PGR P06401 10/20 0.84
NR3C2 P08235 6/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4936648 0.94 NR3C1 (0.92) NR3C1PGRNR3C2
SCHEMBL4438357 0.92 NR3C1 (0.89) NR3C1PGRNR3C2
SCHEMBL4619029 0.91 NR3C1 (1.00) NR3C1PGRNR3C2
SCHEMBL4433653 0.91 NR3C1 (0.82) NR3C1PGRNR3C2
SCHEMBL4427968 0.91 NR3C1 (0.87) NR3C1PGRNR3C2
SCHEMBL4945862 0.90 NR3C1 (0.85) NR3C1PGRNR3C2
SCHEMBL4940012 0.90 PGR (0.68) NR3C1PGRNR3C2
SCHEMBL1931882 0.89 NR3C1 (0.68) NR3C1PGRNR3C2
SCHEMBL4941961 0.88 NR3C1 (0.83) NR3C1PGRNR3C2
SCHEMBL4936654 0.88 NR3C1 (0.85) NR3C1PGRNR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080171873-A1 Synthesis of selected stereoisomers of certain substituted alcohols BAUSCH & LOMB INCORPORATED 2008-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171873-A1 Synthesis of selected stereoisomers of certain substituted alcohols ADH1A, ADH1C, ADH5 NR3C1 74/4885PGR 3574/4885NR3C2 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.