Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.73 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.44 |
| ▸ | HTR3B | O95264 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 3/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417647 | 0.84 | ALDH1A3 (1.00) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL18519816 | 0.84 | ALDH1A3 (1.00) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11305457 | 0.83 | ALDH1A3 (0.96) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4934676 | 0.82 | ALDH1A1 (0.73) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31494990 | 0.82 | ALDH1A1 (0.73) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL29952847 | 0.81 | ALDH1A1 (0.71) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL15093728 | 0.80 | ALDH1A3 (1.00) | ALDH1A3ALDH3A1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6024911 | 0.78 | ADRB1 (0.49) | ALDH1A3ALDH3A1ADRB1DRD2DRD3 | |
| SCHEMBL3688210 | 0.77 | MAPT (0.76) | ALDH1A3ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL29831886 | 0.77 | HTR3A (0.60) | ADRB1DRD2DRD3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255144-A1 | Acylated Piperidines as Glycine Transporter Inhibitors | GLAXO GROUP LIMITED | 2008-10-16 | — | — | US | disclosed |
| US-20080255144-A1 | Acylated Piperidines as Glycine Transporter Inhibitors | GLAXO GROUP LIMITED | 2008-10-16 | — | — | US | disclosed |
| US-20080255144-A1 | Acylated Piperidines as Glycine Transporter Inhibitors | GLAXO GROUP LIMITED | 2008-10-16 | — | — | US | disclosed |
| EP-1858869-A1 | ACYLATED PIPERIDINES AS GLYCINE TRANSPORTER INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006094842-A1 | ACYLATED PIPERIDIHES AS GLYCINE TRANSPORTER INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255144-A1 | Acylated Piperidines as Glycine Transporter Inhibitors | SLC1A1, SLC6A7, SLC1A2 | ALDH1A3 3060/4885ALDH3A1 1724/4885ADRB1 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.