Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431544 | 0.96 | ALDH1A1 (0.54) | KMT2AALDH1A1HPGDPTPN11TSHR | |
| SCHEMBL4946388 | 0.92 | ALDH1A1 (0.60) | ALDH1A1HPGDPTPN11TSHRPLA2G2D | |
| SCHEMBL4944488 | 0.92 | ALDH1A1 (0.57) | ALDH1A1HPGDPTPN11TSHRPLA2G2D | |
| SCHEMBL4943889 | 0.91 | ALDH1A1 (0.63) | ALDH1A1HPGDPTPN11TSHRPLA2G2D | |
| SCHEMBL3431580 | 0.91 | ALDH1A1 (0.63) | ALDH1A1HPGDPTPN11TSHRPLA2G2D | |
| SCHEMBL21828892 | 0.89 | TSHR (0.62) | CREBBPPOLBCASP6TSHRPTGDR2 | |
| SCHEMBL566516 | 0.83 | POLB (0.66) | KMT2AALDH1A1HPGDPTPN11CREBBP | |
| SCHEMBL1987664 | 0.82 | CA12 (0.67) | ALDH1A1TSHRKDM4ECA12CA1 | |
| SCHEMBL29956605 | 0.82 | CA12 (0.67) | ALDH1A1TSHRKDM4ECA12CA1 | |
| SCHEMBL12492247 | 0.81 | THRA (0.56) | KMT2AALDH1A1HPGDPTPN11CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | claimed |
| US-10702515-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20180169086-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2018-06-21 | — | — | US | disclosed |
| US-9895361-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160184289-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2016-06-30 | — | — | US | disclosed |
| US-9107874-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-8496951-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2013-07-30 | — | — | US | disclosed |
| US-20130035359-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2013-02-07 | — | — | US | disclosed |
| US-8268336-B2 | Compositions containing aromatic aldehydes and their use in treatments | SKINMEDICA, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-8246971-B2 | Compositions containing aromatic aldehydes and their use in treatment | SKINMEDICA, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-8246969-B2 | Use in cosmetics and as topical, transdermal or systemic antiinflammatory pharmaceuticals | SKINMEDICA, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20120190753-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | MERZ AESTHETICS, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120157546-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | MERZ AESTHETICS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20080004354-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENT | CUTANIX CORPORATION | 2008-01-03 | — | — | US | disclosed |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10702515-B2 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | KMT2A 2677/4885ALDH1A1 4/4885HPGD 286/4885 |
| US-20180169086-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | KMT2A 2677/4885ALDH1A1 4/4885HPGD 286/4885 |
| US-20120190753-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | TYR, ALDH2, AOX1 | KMT2A 2677/4885ALDH1A1 4/4885HPGD 286/4885 |
| US-20130035359-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | KMT2A 2677/4885ALDH1A1 4/4885HPGD 286/4885 |
| US-20120157546-A1 | Compositions Containing Aromatic Aldehydes and Their Use in Treatments | TYR, ALDH2, AOX1 | KMT2A 2677/4885ALDH1A1 4/4885HPGD 286/4885 |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | KMT2A 2677/4885ALDH1A1 4/4885HPGD 286/4885 |
| US-20080004354-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENT | TYR, ALDH2, AOX1 | KMT2A 2697/4885ALDH1A1 4/4885HPGD 272/4885 |
| US-20160184289-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | KMT2A 2677/4885ALDH1A1 4/4885HPGD 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.