Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896248 | 0.84 | LMNA (0.47) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL5702382 | 0.83 | SLC6A2 (0.54) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL289556 | 0.83 | PGR (0.53) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL1822406 | 0.83 | PGR (0.53) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL5711629 | 0.81 | NPC1 (0.50) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL11781795 | 0.80 | CES2 (0.49) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL637814 | 0.79 | GPR84 (0.53) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL5711633 | 0.79 | PGR (0.46) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL11274424 | 0.78 | CES1 (0.47) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL2563963 | 0.77 | GPR84 (0.56) | CES1CES2SLC6A2SLC6A3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348071-B2 | Complex fluorene-containing compounds and use | EASTMAN KODAK COMPANY (US) | 2008-03-25 | — | — | US | disclosed |
| US-7285341-B2 | Complex fluorene-containing compounds for use in OLED devices | EASTMAN KODAK COMPANY (US) | 2007-10-23 | — | — | US | disclosed |
| EP-1578887-A2 | COMPLEX FLUORENE-CONTAINING COMPOUNDS FOR USE IN OLED DEVICES | Eastman Kodak Company (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20050202279-A1 | Complex fluorene-containing compounds for use in OLED devices | EASTMAN KODAK COMPANY | 2005-09-15 | — | — | US | disclosed |
| US-6849348-B2 | Complex fluorene-containing compounds | EASTMAN KODAK COMPANY (US) | 2005-02-01 | — | — | US | disclosed |
| US-20040241496-A1 | Complex fluorene-containing compounds and use | EASTMAN KODAK COMPANY | 2004-12-02 | — | — | US | disclosed |
| WO-2004061047-A2 | COMPLEX FLUORENE-CONTAINING COMPOUNDS FOR USE IN ORGANIC LIGHT EMITTING DEVICES | EASTMAN KODAK COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |
| WO-2004061048-A1 | COMPLEX FLUORENE-CONTAINING COMPOUNDS AND ELECTROLUMINESCENT DEVICES | EASTMAN KODAK COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20040131881-A1 | Complex fluorene-containing compounds for use in OLED devices | EASTMAN KODAK COMPANY | 2004-07-08 | — | — | US | disclosed |
| US-20040131880-A1 | Complex fluorene-containing compounds | EASTMAN KODAK COMPANY | 2004-07-08 | — | — | US | disclosed |