Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | DPP4 | P27487 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.67 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.67 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.67 |
| ▸ | GAPDH | P04406 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | STAT6 | P42226 | 1/20 | 0.67 |
| ▸ | PI4KA | P42356 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.67 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.67 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003533 | 0.90 | ADORA1 (0.71) | AHCYADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8328542 | 0.88 | ADORA1 (0.74) | AHCYADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL1934658 | 0.87 | AHCY (0.72) | AHCYADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL3302567 | 0.87 | ADORA1 (0.65) | AHCYADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL4916792 | 0.87 | ADORA1 (0.65) | AHCYADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL3306997 | 0.86 | ADORA1 (0.66) | AHCYADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL873362 | 0.86 | ADORA3 (0.72) | AHCYADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL3698839 | 0.86 | ADORA3 (0.72) | AHCYADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL2793634 | 0.85 | ADORA1 (0.67) | AHCYADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL2270709 | 0.85 | ADORA1 (0.73) | AHCYADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685684-A | Compositions and methods for treating type 1a glycogen storage disease | 比姆医疗股份有限公司 | 2023-09-01 | — | — | CN | disclosed |
| WO-2023114963-A1 | COMPOSITIONS AND METHODS FOR SELECTIVELY LABELING SECONDARY AMINES | EMORY UNIVERSITY (US) | 2023-06-22 | — | — | WO | disclosed |
| CN-115279398-A | Compositions and methods for treating liquid cancers | 比姆医疗股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-114641567-A | Compositions and methods for editing mutations to allow transcription or expression | 比姆医疗股份有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114096666-A | Compositions and methods for treating heme disorders | 比姆医疗股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-114072509-A | Nucleobase editor with reduced off-target of deamination and method of modifying nucleobase target sequence using same | 比姆医疗股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114040970-A | Methods of editing disease-associated genes using adenosine deaminase base editor, including treatment of genetic diseases | 比姆医疗股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-110214183-A | Adenosine nucleobase editing machine and application thereof | 哈佛大学的校长及成员们 | 2019-09-06 | — | — | CN | disclosed |
| CN-109952297-A | Compound | 奥斯陆大学 | 2019-06-28 | — | — | CN | disclosed |
| US-20080168707-A1 | Additive for hydrocarbon fuel and related processes consisting of compounds of adenosine phosphates | ENVIROFUELS LLC (US) | 2008-07-17 | — | — | US | disclosed |
| WO-2007136548-A2 | ADDITIVE FOR HYDROCARBON FUEL AND RELATED PROCESSES CONSISTING OF COMPOUNDS OF ADENOSINE PHOSPHATES | ENVIROFUELS, LLC (US) | 2007-11-29 | — | — | WO | disclosed |
| CN-1032815-C | Selective adenosine receptor agents | MERRELL DOW PHARMA (US) | 1996-09-18 | — | — | CN | disclosed |
| CN-1055181-A | SELECTIVE ADENOSINE RECEPTOR AGENTS | MERRELL DOW PHARMA (US) | 1991-10-09 | — | — | CN | disclosed |
| US-4992535-A | Cardiovascular disorders; side effect reduction | G. D. SEARLE & CO. (US) | 1991-02-12 | — | — | US | disclosed |