Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | DPP4 | P27487 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.64 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.64 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.64 |
| ▸ | GAPDH | P04406 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | STAT6 | P42226 | 1/20 | 0.64 |
| ▸ | PI4KA | P42356 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.64 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.64 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.64 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.64 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302567 | 1.00 | ADORA1 (0.65) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL3306997 | 0.91 | ADORA1 (0.66) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL8003533 | 0.87 | ADORA1 (0.71) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL4944751 | 0.87 | AHCY (0.69) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL3698839 | 0.86 | ADORA3 (0.72) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL873362 | 0.86 | ADORA3 (0.72) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL8328542 | 0.85 | ADORA1 (0.74) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6335984 | 0.85 | ADORA1 (0.70) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL2534140 | 0.84 | EHMT1 (0.70) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL15338536 | 0.83 | ADORA1 (0.74) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020169140-A1 | Combination therapy for reduction of toxicity of chemotherapeutic agents | HOLLIS-EDEN PHARMACEUTICALS, INC. | 2002-11-14 | — | — | US | claimed |
| WO-2002069949-A2 | COMBINATION THERAPY FOR REDUCTION OF TOXYCITY OF CHEMOTHERAPEUTIC AGENTS | PRENDERGAST PATRICK T (IE) | 2002-09-12 | — | — | WO | claimed |
| EP-0355825-A2 | Viral treatment system | Prendergast, Patrick T. (IE) | 1990-02-28 | — | — | EP | claimed |
| US-20080139496-A1 | COMBINATION THERAPY FOR REDUCTION OF TOXICITY OF CHEMOTHERAPEUTIC AGENTS | CASCADE ESTATE LTD. (GB) | 2008-06-12 | — | — | US | disclosed |
| US-20020169140-A1 | Combination therapy for reduction of toxicity of chemotherapeutic agents | HOLLIS-EDEN PHARMACEUTICALS, INC. | 2002-11-14 | — | — | US | disclosed |
| WO-2002069949-A2 | COMBINATION THERAPY FOR REDUCTION OF TOXYCITY OF CHEMOTHERAPEUTIC AGENTS | PRENDERGAST PATRICK T (IE) | 2002-09-12 | — | — | WO | disclosed |
| EP-0462621-A2 | Use of particular compounds for manufacture of pharmaceutical formulations for treatment against various parasites, mycoplasmas, other indications and other infections | Prendergast, Patrick Thomas (IE) | 1991-12-27 | — | — | EP | disclosed |
| EP-0355825-A2 | Viral treatment system | Prendergast, Patrick T. (IE) | 1990-02-28 | — | — | EP | disclosed |