SCHEMBL4945125

SCHEMBL4945125

CCCCC(CC)(CO)CO.OP(O)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7099255 0.91 ALDH1A1 (0.33) FDPSALDH1A1
SCHEMBL251421 0.89 ALDH1A1 (0.38) FDPSALDH1A1
SCHEMBL21161 0.89 ALDH1A1 (0.38) FDPSALDH1A1
SCHEMBL6568311 0.86 ALDH1A1 (0.36) FDPSALDH1A1
SCHEMBL28554930 0.86 ALDH1A1 (0.36) FDPSALDH1A1
SCHEMBL6229516 0.86 FDPS (0.31) FDPS
SCHEMBL2349277 0.84 ALDH1A1 (0.38) FDPSALDH1A1
SCHEMBL2343833 0.84 ALDH1A1 (0.38) FDPSALDH1A1
Benzene SCHEMBL28228638 0.82 ALDH1A1 (0.33) FDPSALDH1A1
1,4-Butanediol SCHEMBL5909563 0.82 SMN1; SMN2 (0.50) FDPSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442732-B2 Hindered amine light stabilizers comprising neoalkanediol phosphites CROMPTON CORPORATION (US) 2008-10-28 US disclosed
US-20060223918-A1 Hindered amine light stabilizers comprising neoalkanediol phosphites ADDIVANT USA, LLC 2006-10-05 US disclosed
US-20050009967-A1 Phosphite stabilizers and methods to preparation and polymer composition thereof CROMPTON CORPORATION 2005-01-13 US disclosed
WO-2004111158-A1 PHOSPHITE STABILIZERS AND METHODS TO PREPARATION AND POLYMER COMPOSITION THEREOF CHEMTURA CORPORATION (US) 2004-12-23 WO disclosed
US-6773624-B2 REACTING GLYCOL SUCH AS PENTAERYTHRITOL WITH PHOSPHORUS TRIHALIDE TO PRODUCE HALO PHOSPHITE ESTER OF GLYCOL, REACTING PRODUCT WITH A PHENOL, REACTING SECOND PRODUCTS COMPRISING ORGANIC PHOSPHITE AND HALO PHOSPHITE WITH METAL PHENOLATE CROMPTON CORPORATION 2004-08-10 US disclosed
US-6747167-B2 REACTING A STERICALLY HINDERED PHENOL AND ACID HALIDE (PCL3) IN THE PRESENCE OF AN AMINE, THEN FURTHER REACTING WITH A CYCLIC ACID ACCEPTOR (DBN, DBU, DMAP OR DABCO) FOR AT LEAST A 98% CONVERSION TO THE PHOSPHITE CROMPTON CORPORATION 2004-06-08 US disclosed
US-20040059151-A1 Process for the preparation of acid esters GENERAL ELECTRIC COMPANY 2004-03-25 US disclosed
EP-0940407-B1 Cyclic bis-phosphites GEN ELECTRIC (US) 2003-12-03 EP disclosed
US-6444836-B1 PURITY; DESORPTION USING AN INERT GAS; REACTING ALCOHOL WITH PHOSPHOROUS COMPOUND GENERAL ELECTRIC COMPANY 2002-09-03 US disclosed
US-6426429-B1 REACTING A GLYCOL WITH A PHOSPHORUS TRI-HALIDE, REACTING THE HALO PHOSPHITE ESTER PRODUCT WITH A PHENOL, AND FURTHER REACTING ITS PRODUCT WITH A METAL PHENOLATE GENERAL ELECTRIC COMPANY 2002-07-30 US disclosed
EP-0940407-A1 Cyclic bis-phosphites GENERAL ELECTRIC COMPANY (US) 1999-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040059151-A1 Process for the preparation of acid esters HAO2, HAO1, DBF4 FDPS 58/4885ALDH1A1 1092/4885
US-20050009967-A1 Phosphite stabilizers and methods to preparation and polymer composition thereof PHOSPHO1, OR51E2, CDIPT FDPS 236/4885ALDH1A1 3363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.