Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033422 | 0.86 | MAPK9 (0.47) | MAPK9MAPK10NPC1RAB9AKDM4E | |
| SCHEMBL5033477 | 0.81 | MAPK9 (0.45) | MAPK9MAPK10NPC1RAB9AKDM4E | |
| SCHEMBL5042890 | 0.81 | MAPK9 (0.46) | MAPK9MAPK10MGLLNPC1RAB9A | |
| SCHEMBL5596710 | 0.80 | ALDH1A1 (0.47) | MAPK9MAPK10NPC1RAB9AKDM4E | |
| SCHEMBL3747871 | 0.79 | MAPK9 (0.42) | MAPK9MAPK10NPC1RAB9AKDM4E | |
| SCHEMBL4949235 | 0.78 | RAB9A (0.44) | MAPK9MAPK10MGLLNPC1RAB9A | |
| SCHEMBL4949154 | 0.77 | MKNK1 (0.47) | MAPK9MAPK10NPC1RAB9AKDM4E | |
| SCHEMBL4952153 | 0.77 | MAPK8 (0.49) | MAPK9MAPK10MGLLRAB9AKDM4E | |
| SCHEMBL4950482 | 0.77 | FNTA (0.42) | MAPK9MAPK10MGLLNPC1RAB9A | |
| SCHEMBL5596354 | 0.75 | SMN1; SMN2 (0.50) | MAPK9MAPK10NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812072-B1 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | ARES TRADING SA (CH) | 2008-10-22 | — | — | EP | disclosed |