Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 4/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952153 | 0.92 | MAPK8 (0.49) | RAB9ASMN1; SMN2CYP1A2CYP3A4TP53 | |
| SCHEMBL5033422 | 0.88 | MAPK9 (0.47) | RAB9ASMN1; SMN2CYP1A2CYP3A4TP53 | |
| SCHEMBL5042890 | 0.84 | MAPK9 (0.46) | RAB9ASMN1; SMN2CYP1A2CYP3A4TP53 | |
| SCHEMBL4950482 | 0.84 | FNTA (0.42) | RAB9ASMN1; SMN2CYP1A2CYP3A4MAPK9 | |
| SCHEMBL5033477 | 0.83 | MAPK9 (0.45) | RAB9ASMN1; SMN2CYP1A2CYP3A4HIF1A | |
| SCHEMBL3747871 | 0.80 | MAPK9 (0.42) | RAB9ASMN1; SMN2CYP1A2CYP3A4MAPK9 | |
| SCHEMBL4948638 | 0.78 | MAPK9 (0.43) | RAB9ASMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL4950093 | 0.75 | LTA4H (0.50) | RAB9ASMN1; SMN2LTA4HMAPK9MAPK10 | |
| SCHEMBL5596710 | 0.75 | ALDH1A1 (0.47) | RAB9ASMN1; SMN2TP53MAPK9MAPK10 | |
| SCHEMBL7396523 | 0.74 | ILK (0.41) | RAB9ASMN1; SMN2CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812072-B1 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | ARES TRADING SA (CH) | 2008-10-22 | — | — | EP | disclosed |
| EP-1812072-A2 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | Ares Trading S.A. (CH) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006053882-A2 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | ARES TRADING S.A. (CH) | 2006-05-26 | — | — | WO | disclosed |