Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ILK | Q13418 | 2/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949235 | 0.92 | RAB9A (0.44) | MAPK8MAPK9MAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL5033422 | 0.87 | MAPK9 (0.47) | MAPK8MAPK9MAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL4950093 | 0.84 | LTA4H (0.50) | MAPK8MAPK9MAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL5042890 | 0.83 | MAPK9 (0.46) | MAPK8MAPK9MAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL4950482 | 0.82 | FNTA (0.42) | MAPK9MAPK10SMN1; SMN2ALDH1A1MGLL | |
| SCHEMBL5033477 | 0.81 | MAPK9 (0.45) | MAPK8MAPK9MAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL3747871 | 0.79 | MAPK9 (0.42) | MAPK8MAPK9MAPK10SMN1; SMN2ALDH1A1 | |
| SCHEMBL4948638 | 0.77 | MAPK9 (0.43) | MAPK9MAPK10SMN1; SMN2ALDH1A1MGLL | |
| SCHEMBL5596770 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MGLLILKGHSR | |
| SCHEMBL3747858 | 0.74 | MAPK10 (0.86) | MAPK8MAPK9MAPK10SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812072-B1 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | ARES TRADING SA (CH) | 2008-10-22 | — | — | EP | disclosed |