Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ILK | Q13418 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17709604 | 0.82 | MAPK10 (0.56) | MKNK1MKNK2NPC1RAB9AMAPK8 | |
| SCHEMBL5596710 | 0.80 | ALDH1A1 (0.47) | NPC1RAB9AMAPK9MAPK10ILK | |
| SCHEMBL4948638 | 0.77 | MAPK9 (0.43) | NPC1RAB9AMAPK9MAPK10CYP3A4 | |
| SCHEMBL4946974 | 0.77 | ALDH1A1 (0.40) | NPC1RAB9AILKKDM4EALDH1A1 | |
| SCHEMBL4950093 | 0.76 | LTA4H (0.50) | MKNK1RAB9AMAPK8MAPK9MAPK10 | |
| SCHEMBL5596354 | 0.75 | SMN1; SMN2 (0.50) | NPC1RAB9AMAPK9MAPK10KDM4E | |
| SCHEMBL5033422 | 0.75 | MAPK9 (0.47) | NPC1RAB9AMAPK8MAPK9MAPK10 | |
| SCHEMBL4950482 | 0.75 | FNTA (0.42) | NPC1RAB9AMAPK9MAPK10CYP3A4 | |
| SCHEMBL4949235 | 0.73 | RAB9A (0.44) | NPC1RAB9AMAPK8MAPK9MAPK10 | |
| SCHEMBL3742492 | 0.72 | MAPK10 (0.71) | MKNK1MKNK2NPC1RAB9AMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812072-B1 | BENZOTHIAZOLE FORMULATIONS AND USE THEREOF | ARES TRADING SA (CH) | 2008-10-22 | — | — | EP | disclosed |