SCHEMBL7040376

SCHEMBL7040376

Cc1cc2cc(C(=O)O)[nH]c2cc1O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.73
PIN1 Q13526 1/20 0.57
SMAD3 P84022 1/20 0.54
EIF4A3 P38919 2/20 0.50
KDM4E B2RXH2 2/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
SRD5A2 P31213 2/20 0.49
F7 P08709 1/20 0.49
F3 P13726 1/20 0.49
PDPK1 O15530 1/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49
APEX1 P27695 1/20 0.49
CYP2C19 P33261 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MAPT P10636 1/20 0.49
DAO P14920 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7682186 0.87 GPR35 (0.63) GPR35PIN1SMAD3EIF4A3KDM4E
SCHEMBL49512 0.85 GPR35 (1.00) GPR35PIN1SMAD3EIF4A3KDM4E
SCHEMBL7092509 0.81 GPR35 (0.56) GPR35PIN1SMAD3EIF4A3KDM4E
SCHEMBL765246 0.81 EIF4A3 (0.60) GPR35PIN1SMAD3EIF4A3KDM4E
SCHEMBL9442095 0.80 GPR35 (0.69) GPR35PIN1SMAD3EIF4A3KDM4E
SCHEMBL24149191 0.79 GPR35 (0.69) GPR35PIN1SMAD3EIF4A3KDM4E
SCHEMBL12596876 0.79 GPR35 (0.53) GPR35PIN1SMAD3EIF4A3KDM4E
SCHEMBL19332155 0.79 GPR35 (0.73) GPR35PIN1SMAD3EIF4A3KDM4E
SCHEMBL3361096 0.78 GPR35 (0.67) GPR35PIN1SMAD3EIF4A3KDM4E
SCHEMBL30779684 0.78 GPR35 (0.67) GPR35PIN1SMAD3EIF4A3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0597022-B2 PROCESS FOR THE TEMPORARY DYEING OF KERATIN FIBRES INVOLVING AN INSOLUBLE PIGMENT OBTAINED BY THE OXIDATIVE POLYMERISATION OF INDOLE DERIVATIVES OREAL (FR) 1999-11-17 EP claimed
US-5874091-A PROTECTION OF SKIN AND HAIR AGAINST ULTRAVIOLET RADIATION AND FOR PIGMENTATION OF THE SKIN AND HAIR; HOMOGENEOUS AQUEOUS DISPERSION OF LAMELLAR AND ENCAPSULATING VESICLES; STORAGE STABILITY; STORING MELANIN PIGMENT IN THE STRATUM CORNEUM. L'OREAL (FR) 1999-02-23 US claimed
EP-0587837-B1 Cosmetic composition containing melanistic pigments in association with certain tocopherols, and method for protecting the skin, the hair, the mucous membranes and cosmetic compositions OREAL (FR) 1998-06-03 EP claimed
EP-0544874-B1 METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS OREAL (FR) 1998-04-08 EP claimed
US-5695747-A APPLYING TO THE SKIN OR HAIR AND ULTRAVIOLET PROETECTION AGENT L'OREAL (FR) 1997-12-09 US claimed
US-5670099-A PREPARING A DISPERSION OF LIPIDIC VESICLES FROM ATLEAST ONE LIPID, AN AQUEOUS PHASE ENCAPSULATED IN VESICLE, DISSOLVING POLYMERIZABLE INDOLIC OR INDOLINIC MONOMER WITH A POLYMERIZATION AGENT, REACTS WITH MONOMER FORMS PARTICLES L'OREAL (FR) 1997-09-23 US claimed
US-5645609-A Compositions which contain and processes which use an insoluble pigment obtained by the oxidative polymerization of indole derivatives for the temporary dyeing of keratinous fibers L'OREAL (FR) 1997-07-08 US claimed
EP-0575603-B1 PRODUCT BASED ON COLOURED MINERAL PARTICLES INCLUDING A MELANIC PIGMENT, PROCESS FOR PREPARING SAME AND APPLICATION IN COSMETICS OREAL (FR) 1996-10-23 EP claimed
US-5547658-A Cosmetic composition containing melaninlike pigments in combination with certain tocopherols, and process for protecting the skin, hair, mucosae and cosmetic compositions L'OREAL (FR) 1996-08-20 US claimed
EP-0597022-B1 PROCESS FOR THE TEMPORARY DYEING OF KERATIN FIBRES INVOLVING AN INSOLUBLE PIGMENT OBTAINED BY THE OXIDATIVE POLYMERISATION OF INDOLE DERIVATIVES OREAL (FR) 1996-04-03 EP claimed
WO-1993013743-A1 PRODUCT BASED ON COLOURED MINERAL PARTICLES INCLUDING A MELANIC PIGMENT, PROCESS FOR PREPARING SAME AND APPLICATION IN COSMETICS L'OREAL (FR) 1993-07-22 WO claimed
EP-0544874-A1 METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS L'OREAL (FR) 1993-06-09 EP claimed
US-5205837-A Formed in situ by oxidation of indole compound L'OREAL (FR) 1993-04-27 US claimed
WO-1993005754-A1 FINE DISPERSION OF MELANIC PIGMENTS, ITS PREPARATION AND UTILISATION IN COSMETICS L'OREAL (FR) 1993-04-01 WO claimed
WO-1993002655-A1 PROCESS FOR THE TEMPORARY DYEING OF KERATIN FIBRES INVOLVING AN INSOLUBLE PIGMENT OBTAINED BY THE OXIDATIVE POLYMERISATION OF INDOLE DERIVATIVES L'OREAL (FR) 1993-02-18 WO claimed
WO-1993000068-A1 METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS L'OREAL (FR) 1993-01-07 WO claimed
EP-0518773-A1 Cosmetic composition containing a blend of metallic oxids nanopigments and melanic pigments L'OREAL (FR) 1992-12-16 EP claimed
EP-0504347-A1 COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS. OREAL (FR) 1992-09-23 EP claimed
WO-1992005761-A1 COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS L'OREAL (FR) 1992-04-16 WO claimed
EP-0467767-A1 Product based on flaky particles containing melanine pigment and process for their preparation L'OREAL (FR) 1992-01-22 EP claimed