Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140782 | 0.85 | CHRM1 (0.41) | CHRM1DRD2DRD4DRD3 | |
| SCHEMBL727285 | 0.82 | KDM4E (0.40) | CHRM1DRD2DRD4DRD3 | |
| SCHEMBL728727 | 0.73 | LMNA (0.32) | — | |
| SCHEMBL1140756 | 0.68 | ALDH1A1 (0.47) | — | |
| SCHEMBL8771675 | 0.66 | DRD2 (0.39) | CHRM1DRD2DRD4DRD3 | |
| SCHEMBL6086566 | 0.64 | VHL (0.50) | CHRM1DRD2DRD4DRD3 | |
| SCHEMBL1091438 | 0.64 | PGR (0.45) | CHRM1DRD2DRD4DRD3 | |
| SCHEMBL6086547 | 0.63 | KDM4E (0.59) | — | |
| SCHEMBL8606021 | 0.63 | ALDH1A1 (0.37) | — | |
| SCHEMBL31669018 | 0.63 | CHRM1 (0.43) | CHRM1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648397-A4 | EX VIVO PROGENITOR AND STEM CELL EXPANSION FOR USE IN THE TREATMENT OF DISEASE OF ENDODERMALLY-DERIVED ORGANS | GAMIDA CELL LTD (IL) | 2008-05-21 | — | — | EP | disclosed |
| EP-1649007-A4 | METHODS FOR EX-VIVO EXPANDING STEM/PROGENITOR CELLS | GAMIDA CELL LTD (IL) | 2008-05-14 | — | — | EP | disclosed |
| EP-1649007-A2 | METHODS FOR EX-VIVO EXPANDING STEM/PROGENITOR CELLS | Gamida Cell Ltd. (IL) | 2006-04-26 | — | — | EP | disclosed |
| EP-1648397-A2 | EX VIVO PROGENITOR AND STEM CELL EXPANSION FOR USE IN THE TREATMENT OF DISEASE OF ENDODERMALLY-DERIVED ORGANS | Gamida Cell Ltd. (IL) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005007073-A2 | EX VIVO PROGENITOR AND STEM CELL EXPANSION FOR USE IN THE TREATMENT OF DISEASE OF ENDODERMALLY-DERIVED ORGANS | GAMIDA-CELL LTD. (IL) | 2005-01-27 | — | — | WO | disclosed |
| WO-2005007799-A2 | METHODS FOR EX-VIVO EXPANDING STEM/PROGENITOR CELLS | GAMIDA-CELL LTD. (IL) | 2005-01-27 | — | — | WO | disclosed |