Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.65 |
| ▸ | CA2 | P00918 | 6/20 | 0.65 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.65 |
| ▸ | PARP1 | P09874 | 1/20 | 0.65 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.65 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.65 |
| ▸ | CES2 | O00748 | 2/20 | 0.64 |
| ▸ | CES1 | P23141 | 2/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954760 | 0.88 | CA1 (0.68) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL18687125 | 0.86 | CA1 (0.65) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL272999 | 0.79 | CA1 (0.57) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL201761 | 0.79 | PARP10 (1.00) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL41284 | 0.79 | CA1 (0.68) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL14507040 | 0.78 | CES2 (1.00) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL51509 | 0.78 | RXFP1 (0.79) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL9418310 | 0.78 | RXFP1 (0.79) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL557152 | 0.78 | CES2 (1.00) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL30420427 | 0.78 | CA1 (0.55) | CA1CA2PARP10PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008004117-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-01-10 | — | — | WO | claimed |
| US-20080076847-A1 | Polymerizable compositions with acylgermanes as initiatiors | IVOCLAR VIVADENT AG (LI) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076847-A1 | Polymerizable compositions with acylgermanes as initiatiors | NR1I3, NR4A1, NR1I2 | CA1 2753/4885CA2 3675/4885PARP10 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.